Intestinal bile acids provide a surmountable barrier against C. difficile TcdB-induced disease pathogenesis
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2301252120
Abstract: Significance Clostridioides difficile is the leading cause of hospital-acquired diarrhea worldwide. While TcdB, the primary virulence determinant of C. difficile, is known to be required for the intestinal symptoms associated with infection, asymptomatic carriage of… read more here.
Keywords: tcdb; difficile; bile acids; acids provide ... See more keywords