Salivary gland cell aggregates are derived from self-organization of acinar lineage cells.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2018.10.017
Abstract: OBJECTIVE The objective of this study was to characterize the mechanism by which salivary gland cells (SGC) aggregate in vitro. DESIGN Timelapse microscopy was utilized to analyze the process of salivary gland aggregate formation using… read more here.
Keywords: acinar; gland cell; salivary gland; gland ... See more keywords
Integrative Genomic Analysis of Coincident Cancer Foci Implicates CTNNB1 and PTEN Alterations in Ductal Prostate Cancer.
Sign Up to like & getrecommendations! Published in 2017 at "European urology focus"
DOI: 10.1016/j.euf.2017.12.003
Abstract: BACKGROUND Ductal adenocarcinoma of the prostate is an aggressive subtype, with high rates of biochemical recurrence and overall poor prognosis. It is frequently found coincident with conventional acinar adenocarcinoma. The genomic features driving evolution to… read more here.
Keywords: acinar; prostate cancer; cancer; adenocarcinoma ... See more keywords
Adult Pancreatic Acinar Progenitor-like Populations in Regeneration and Cancer.
Sign Up to like & getrecommendations! Published in 2020 at "Trends in molecular medicine"
DOI: 10.1016/j.molmed.2020.04.003
Abstract: The bulk of the pancreas primarily comprises long-lived acinar cells that are not considered a bona fide source for stem cells. However, certain acinar subpopulations have a repopulating capacity during regeneration, raising the hypothesis as… read more here.
Keywords: acinar; regeneration; like populations; cancer ... See more keywords
PROSTATIC DUCTAL ADENOCARCINOMA CONTROLLED FOR CANCER GRADE AND TUMOR VOLUME DOES NOT HAVE AN INDEPENDENT EFFECT ON ADVERSE RADICAL PROSTATECTOMY OUTCOMES COMPARED TO USUAL ACINAR PROSTATIC ADENOCARCINOMA.
Sign Up to like & getrecommendations! Published in 2019 at "Urology"
DOI: 10.1016/j.urology.2019.10.014
Abstract: OBJECTIVE To study if prostatic ductal adenocarcinoma (PDA) controlled by Grade Group (GG), PSA, and tumor volume (TV) is an independent predictor of adverse radical prostatectomy (RP) outcomes. MATERIALS One-hundred-and-twenty-eight PDA and 1,141 acinar continuous… read more here.
Keywords: acinar; pda; prostatic ductal; effect ... See more keywords
Enhanced proliferation of pancreatic acinar cells in MRL/MpJ mice is driven by severe acinar injury but independent of inflammation
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-27422-0
Abstract: Adult pancreatic acinar cells have the ability to re-enter the cell cycle and proliferate upon injury or tissue loss. Despite this mitotic ability, the extent of acinar proliferation is often limited and unable to completely… read more here.
Keywords: acinar; mpj mice; proliferation; mrl mpj ... See more keywords
Metastatic mixed acinar‐neuroendocrine carcinoma of the pancreas treated by a multidisciplinary team: A case report and brief review of the literature
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Digestive Diseases"
DOI: 10.1111/1751-2980.12752
Abstract: Ranked the fourth or fifth most common cause of cancer globally, pancreatic cancer is recognized as "the king of cancer" for the high malignant potential (1). Pancreatic cancer develops from either the endocrine (islet cell)… read more here.
Keywords: acinar; mixed acinar; metastatic mixed; cancer ... See more keywords
Primary Pure Pancreatic -Type Acinar Cell Carcinoma of the Stomach: A Rare Entity with a Difficult Diagnosis and Review of the Literature
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Surgical Pathology"
DOI: 10.1177/10668969211065763
Abstract: Acinar cell carcinoma is an uncommon tumour, representing only 1% to 2% of all exocrine pancreatic tumours. Pancreatic-type acinar cell carcinoma can occur in other organs, including the stomach, but it is extraordinarily rare. We… read more here.
Keywords: cell carcinoma; cell; pancreatic type; acinar ... See more keywords
Hypoxia-induced pulmonary vasoconstriction of intra-acinar arteries is impaired in NADPH oxidase 4 gene-deficient mice
Sign Up to like & getrecommendations! Published in 2018 at "Pulmonary Circulation"
DOI: 10.1177/2045894018808240
Abstract: We show that genetic deficiency of the reactive oxygen species generating enzyme NADPH oxidase 4 (NOX4) impairs hypoxic pulmonary vasoconstriction in small (25–40 µm) intra-acinar, but not pre-acinar, arteries in murine precision cut lung slices. These… read more here.
Keywords: pulmonary vasoconstriction; intra acinar; acinar; nadph oxidase ... See more keywords
Pathological examination of spontaneous vacuolation of pancreatic acinar cells in mice
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Toxicologic Pathology"
DOI: 10.1293/tox.2018-0065
Abstract: Pancreatic acinar cell vacuolation is spontaneously observed in mice; however, the lesion is rare and has not been well documented. Herein, we present a detailed pathological examination of this lesion. Vacuoles in pancreatic acinar cells… read more here.
Keywords: pancreatic acinar; acinar; vacuolation pancreatic; acinar cells ... See more keywords
An unusual case of primary acinar cell carcinoma of the liver and its treatment.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of gastrointestinal oncology"
DOI: 10.21037/jgo.2019.07.01
Abstract: Acinar cell carcinoma (ACC) is an epithelial neoplasm characterized by morphological features similar to acinar cells found in exocrine glands. Most cases of hepatic ACC reveal evidence of pancreatic exocrine enzyme production and are considered… read more here.
Keywords: acc; acinar; case; liver ... See more keywords
MFG-E8 Maintains Cellular Homeostasis by Suppressing Endoplasmic Reticulum Stress in Pancreatic Exocrine Acinar Cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.803876
Abstract: Excessive endoplasmic reticulum (ER) stress contributes significantly to the pathogenesis of exocrine acinar damage in acute pancreatitis. Our previous study found that milk fat globule EGF factor 8 (MFG-E8), a lipophilic glycoprotein, alleviates acinar cell… read more here.
Keywords: stress; acinar cells; exocrine acinar; stress pancreatic ... See more keywords