Abstract 953: Atypical chemokine receptor 1 (ACKR1/DARC) expressing tumors are associated with distinct recruitment of immune cells and increased pro-inflammatory chemokines
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.am2017-953
Abstract: Interactions between chemokines and their receptors can improve a host’s anti-tumor response by influencing the targeted migration of immune cells via a chemokine gradient. Atypical Chemokine Receptor 1 (ACKR1/DARC), a genetically diverse transmembrane GPCR, acts… read more here.
Keywords: ackr1; inflammatory chemokines; expression; immune cells ... See more keywords
Endothelial ACKR1 is induced by neutrophil contact and down-regulated by secretion in extracellular vesicles
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DOI: 10.3389/fimmu.2023.1181016
Abstract: Atypical chemokine receptor-1 (ACKR1), previously known as the Duffy antigen receptor for chemokines, is a widely conserved cell surface protein that is expressed on erythrocytes and the endothelium of post-capillary venules. In addition to being… read more here.
Keywords: extracellular vesicles; endothelial ackr1; contact; ackr1 ... See more keywords