The Atypical Chemokine Receptor ACKR2 is Protective Against Sepsis
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DOI: 10.1097/shk.0000000000000969
Abstract: ABSTRACT Sepsis is a systemic inflammatory response as a result of uncontrolled infections. Neutrophils are the first cells to reach the primary sites of infection, and chemokines play a key role in recruiting neutrophils. However,… read more here.
Keywords: sepsis; ackr2; atypical chemokine; mice ... See more keywords
The scavenging chemokine receptor ACKR2 has a significant impact on acute mortality rate and early lesion development after traumatic brain injury
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DOI: 10.1371/journal.pone.0188305
Abstract: The atypical chemokine receptor ACKR2 promotes resolution of acute inflammation by operating as a scavenger receptor for inflammatory CC chemokines in several experimental models of inflammatory disorders, however its role in the brain remains unclear.… read more here.
Keywords: ackr2; mortality; brain; expression ... See more keywords
CXCL14 promotes metastasis of non-small cell lung cancer through ACKR2-depended signaling pathway
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DOI: 10.7150/ijbs.79438
Abstract: Background: Lung cancer is a malignant tumor with metastatic potential. Chemokine ligand 14 (CXCL14) has been reported to be associated with different cancer cell migration and invasion. However, few studies have explored the function of… read more here.
Keywords: metastasis; lung cancer; ackr2; cxcl14 ... See more keywords