aCLS cancers: genomic and epigenetic changes transform the cell of origin of cancer into a tumorigenic pathogen of unicellular organization and lifestyle.
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DOI: 10.1016/j.gene.2019.144174
Abstract: At least 1/3 of all acquired solid cancers produce unusual cyst-like structures (CLSs , PGCCs) with simultaneous loss of p53 function. However, p53 deficiency or accumulated mutations are not the causes of aCLS cancers. The… read more here.
Keywords: acls cancers; cell origin; origin cancer; cancer ... See more keywords