Surfactin-oleogel with therapeutic potential for inflammatory acne vulgaris induced by Propionibacterium acnes.
Sign Up to like & getrecommendations! Published in 2021 at "Applied microbiology and biotechnology"
DOI: 10.1007/s00253-021-11719-8
Abstract: Accumulating evidence suggested that suppression of Propionibacterium acnes-induced inflammation was a promising strategy to alleviate acne vulgaris. This study evaluated the alleviating effect of surfactin-oleogel on P. acnes-induced inflammatory acne vulgaris in mice. Epidermis morphology… read more here.
Keywords: surfactin oleogel; acne vulgaris; acnes induced;
Oligochitosan as a potential anti-acne vulgaris agent: combined antibacterial effects against Propionibacterium acnes
Sign Up to like & getrecommendations! Published in 2017 at "Food Science and Biotechnology"
DOI: 10.1007/s10068-017-0118-y
Abstract: To develop an antibacterial treatment for acne vulgaris using natural substance with few side effects, we investigated the antibacterial activities of oligochitosan against acne-related bacteria, particularly Propionibacterium acnes. Oligochitosan showed potent antibacterial effect on P.… read more here.
Keywords: propionibacterium acnes; combination; acne vulgaris; acnes oligochitosan ... See more keywords
Skin Microbiota in Non-inflammatory and Inflammatory Lesions of Acne Vulgaris: The Underlying Changes within the Pilosebaceous Unit.
Sign Up to like & getrecommendations! Published in 2021 at "Mycopathologia"
DOI: 10.1007/s11046-021-00586-6
Abstract: Acne vulgaris is a common chronic inflammatory skin disease of the pilosebaceous unit. Clinical manifestations include seborrhea, non-inflammatory lesions, inflammatory lesions, or scar formation. Fourteen eligible participants of either sex, aged 18-28 years old, with mild… read more here.
Keywords: inflammatory lesions; non inflammatory; inflammatory inflammatory; acne vulgaris ... See more keywords
Efficacy of Modified Qufeng Runmian Powder (加减祛风润面散) on Acne Vulgaris with Syndromes of Dampness and Blood Stasis: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Sign Up to like & getrecommendations! Published in 2020 at "Chinese Journal of Integrative Medicine"
DOI: 10.1007/s11655-020-3214-4
Abstract: Objective To evaluate the efficacy and safety of a Chinese medicine (CM) Modified Qufeng Runmian Powder (加减祛风润面散, MQFRMP) for the treatment of acne vulgaris with CM syndromes of dampness and blood stasis. Methods In this… read more here.
Keywords: blood stasis; dampness blood; treatment; group ... See more keywords
Nano-Therapeutics to Treat Acne Vulgaris.
Sign Up to like & getrecommendations! Published in 2022 at "Indian journal of microbiology"
DOI: 10.1007/s12088-022-01001-4
Abstract: Nanotechnology is a novel approach to dermatologic treatment. Nanomaterials are materials typically defined as less than 100 nm in size. As this size approaches molecular dimensions, the chemical and physical properties vastly change due to a… read more here.
Keywords: treat acne; acne vulgaris; nano therapeutics; nanotechnology ... See more keywords
Oral Antibacterial Therapy for Acne Vulgaris: An Evidence-Based Review
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Clinical Dermatology"
DOI: 10.1007/s40257-017-0267-z
Abstract: BackgroundTo some degree, acne vulgaris affects nearly every individual worldwide. Oral antibiotic therapy is routinely prescribed for the treatment of moderate to severe inflammatory acne; however, long-term use of oral antibiotics for acne may have… read more here.
Keywords: oral antibiotics; efficacy; evidence; acne vulgaris ... See more keywords
Clascoterone: First Approval
Sign Up to like & getrecommendations! Published in 2020 at "Drugs"
DOI: 10.1007/s40265-020-01417-6
Abstract: Clascoterone (Winlevi®) is an androgen receptor inhibitor being developed as a topical cream and solution by Cassiopea (a spin-out company of Cosmo Pharmaceuticals) for the treatment of androgen-dependent skin disorders, including androgenetic alopecia and acne… read more here.
Keywords: androgen; first approval; treatment; acne vulgaris ... See more keywords
Topical Clascoterone: The First Novel Agent for Acne Vulgaris in 40 Years.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical therapeutics"
DOI: 10.1016/j.clinthera.2021.08.007
Abstract: PURPOSE Acne vulgaris is a ubiquitous condition in men and women starting in adolescence. It is often persistent and refractory to multiple treatment methods. Although multiple medications may be used on- or off-label for treatment,… read more here.
Keywords: first novel; novel mechanism; treatment; acne vulgaris ... See more keywords
P.2.033 Self-esteem and mental health in adolescents with acne vulgaris
Sign Up to like & getrecommendations! Published in 2018 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2017.12.072
Abstract: Introduction Acne Vulgaris is a dermatological genetic-hormonal illness, self-limited, in pilosebaceous locations, with formation of comedones, papules and cysts in which evolution to a greater inflammatory process is added, leading to formation of pustules and… read more here.
Keywords: acne vulgaris; mental health; self esteem;
Olumacostat glasaretil, a novel topical sebum inhibitor, in the treatment of acne vulgaris: A phase IIa, multicenter, randomized, vehicle‐controlled study
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Academy of Dermatology"
DOI: 10.1016/j.jaad.2016.08.053
Abstract: Background: Olumacostat glasaretil (OG) inhibits acetyl‐coenzyme A carboxylase, the enzyme responsible for the first, rate‐limiting step in de novo fatty acid synthesis. OG inhibited in vitro human sebocyte lipid production and reduced in vivo sebaceous… read more here.
Keywords: treatment; vehicle; olumacostat glasaretil; acne vulgaris ... See more keywords
Will the polyphenol and adapalene combination be a good strategy on acne vulgaris?
Sign Up to like & getrecommendations! Published in 2019 at "Medical hypotheses"
DOI: 10.1016/j.mehy.2019.109409
Abstract: Acne vulgaris is a common disease which affects about 85% of the population. Various topical drugs are available, but the retinoid derivatives are mostly taken into consideration. They are used as a first-line treatment drugs.… read more here.
Keywords: combination; good strategy; adapalene combination; acne vulgaris ... See more keywords