Licochalcone A attenuates acne symptoms mediated by suppression of NLRP3 inflammasome
Sign Up to like & getrecommendations! Published in 2018 at "Phytotherapy Research"
DOI: 10.1002/ptr.6195
Abstract: Activation of the NACHT, LRR and PYD domains‐containing protein 3 (NLRP3) inflammasome by Propionibacterium acnes (P. acnes) is critical for inducing inflammation and aggravating the development of acne lesions. We searched for available small‐molecule inhibitors… read more here.
Keywords: inflammasome licochalcone; licochalcone; nlrp3 inflammasome; acnes induced ... See more keywords
Surfactin-oleogel with therapeutic potential for inflammatory acne vulgaris induced by Propionibacterium acnes.
Sign Up to like & getrecommendations! Published in 2021 at "Applied microbiology and biotechnology"
DOI: 10.1007/s00253-021-11719-8
Abstract: Accumulating evidence suggested that suppression of Propionibacterium acnes-induced inflammation was a promising strategy to alleviate acne vulgaris. This study evaluated the alleviating effect of surfactin-oleogel on P. acnes-induced inflammatory acne vulgaris in mice. Epidermis morphology… read more here.
Keywords: surfactin oleogel; acne vulgaris; acnes induced;
Polyphyllin I Inhibits Propionibacterium acnes-Induced Inflammation In Vitro
Sign Up to like & getrecommendations! Published in 2018 at "Inflammation"
DOI: 10.1007/s10753-018-0870-z
Abstract: Propionibacterium acnes (P. acnes) has been implicated in the progression of acne inflammation. Because current acne medications have various side effects, it is necessary to explore alternative medications possessing anti-inflammatory activity against P. acnes. We… read more here.
Keywords: propionibacterium acnes; induced inflammation; heat killed; inflammation ... See more keywords
Inhibitory Effect of Quercetin on Propionibacterium acnes-induced Skin Inflammation.
Sign Up to like & getrecommendations! Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2021.107557
Abstract: Quercetin is a well-known antioxidant and a plant polyphenolic of flavonoid group found in many fruits, leaves, and vegetables. Propionibacterium acnes is a key skin pathogen involved in the progression of acne inflammation. Although quercetin… read more here.
Keywords: propionibacterium acnes; inflammation; skin inflammation; induced skin ... See more keywords
Influence of lactoferrin on Propionibacterium acnes‐induced inflammation in vitro and in vivo
Sign Up to like & getrecommendations! Published in 2020 at "Dermatologic Therapy"
DOI: 10.1111/dth.14483
Abstract: Lactoferrin (LF) is a monomer glycoprotein in the mammalian colostrum that has multiple biological activities and a high affinity for iron ions. Not only does it have strong antibacterial activity, it also can regulate the… read more here.
Keywords: propionibacterium acnes; vitro vivo; induced inflammation; inflammation ... See more keywords
Fucoxanthin ameliorates Propionibacterium acnes-induced ear inflammation in mice by modulating the IκBα/NF-κB signaling pathway and inhibiting NF-κB nuclear translocation
Sign Up to like & getrecommendations! Published in 2025 at "PLOS One"
DOI: 10.1371/journal.pone.0322950
Abstract: Background Acne vulgaris, a chronic inflammatory skin disorder, represents a pivotal research area in dermatology. Although fucoxanthin, a marine-derived carotenoid, displays potent anti-inflammatory activity, its therapeutic potential in acne pathogenesis remains underexplored. Objective This study… read more here.
Keywords: mice; propionibacterium acnes; inflammation; nuclear translocation ... See more keywords
Cutibacterium acnes Infection Induces Type I Interferon Synthesis Through the cGAS-STING Pathway
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.571334
Abstract: Cutibacterium (previously Propionibacterium) acnes is an anaerobic, Gram-positive commensal of the human body. The bacterium has been associated with a variety of diseases, including acne vulgaris, prosthetic joint infections, prostate cancer, and sarcoidosis. The accumulation… read more here.
Keywords: type interferon; cgas sting; sting pathway; acnes induced ... See more keywords
Investigating Propionibacterium acnes antibiotic susceptibility and response to bacteriophage in vitro and in vivo
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2024.1424849
Abstract: Introduction A total of 94 Propionibacterium acnes (P. acnes) isolates were obtained from a hospital in Beijing to evaluate their susceptibility to erythromycin, clarithromycin, doxycycline, and minocycline. As well as the determination of the effectiveness… read more here.
Keywords: erythromycin clarithromycin; susceptibility; propionibacterium acnes; culture ... See more keywords
Peiminine Exerts Its Anti-Acne Effects by Regulating the NF-κB Pathway
Sign Up to like & getrecommendations! Published in 2024 at "Antioxidants"
DOI: 10.3390/antiox13010131
Abstract: Peiminine is the main natural alkaloid compound extracted from the Chinese herb Fritillaria. Although peiminine is known for its antioxidant and anti-inflammatory effects in conditions such as mastitis and arthritis, its impact on inflammation induced… read more here.
Keywords: peiminine; anti acne; acne effects; peiminine exerts ... See more keywords
Suppression of Propionibacterium acnes-Induced Skin Inflammation by Laurus nobilis Extract and Its Major Constituent Eucalyptol
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms20143510
Abstract: Acne is an inflammatory skin disorder in puberty with symptoms including papules, folliculitis, and nodules. Propionibacterium acnes (P. acnes) is the main anaerobic bacteria that cause acne. It is known to proliferate within sebum-blocked skin… read more here.
Keywords: propionibacterium acnes; inflammation; skin inflammation; nobilis extract ... See more keywords
Micro-Current Stimulation Suppresses Inflammatory Responses in Peptidoglycan-Treated Raw 264.7 Macrophages and Propionibacterium acnes-Induced Skin Inflammation via TLR2/NF-κB Signaling Pathway
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23052508
Abstract: Acne is a common inflammatory disorder of the human skin and a multifactorial disease caused by the sebaceous gland and Propionibacterium acnes (P. acnes). This study aimed to evaluate the anti-inflammatory effect of micro-current stimulation… read more here.
Keywords: acnes induced; tlr2 signaling; induced skin; treated raw ... See more keywords