Prenatal exposure to PCBs in Cyp1a2 knock‐out mice interferes with F1 fertility, impairs long‐term potentiation, reduces acoustic startle and impairs conditioned freezing contextual memory with minimal transgenerational effects
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.3751
Abstract: Polychlorinated biphenyls (PCBs) are toxic environmental pollutants. Humans are exposed to PCB mixtures via contaminated food or water. PCB exposure causes adverse effects in adults and after exposure in utero. PCB toxicity depends on the… read more here.
Keywords: acoustic startle; exposure; pcbs; pcb ... See more keywords
Preimmunization with a heat-killed preparation of Mycobacterium vaccae enhances fear extinction in the fear-potentiated startle paradigm
Sign Up to like & getrecommendations! Published in 2017 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2017.08.014
Abstract: The hygiene hypothesis or "Old Friends" hypothesis proposes that inflammatory diseases are increasing in modern urban societies, due in part to reduced exposure to microorganisms that drive immunoregulatory circuits, and a failure to terminate inappropriate… read more here.
Keywords: acoustic startle; fear; extinction; fear potentiated ... See more keywords
Neuroplasticity in the acoustic startle reflex in larval zebrafish
Sign Up to like & getrecommendations! Published in 2019 at "Current Opinion in Neurobiology"
DOI: 10.1016/j.conb.2018.10.004
Abstract: Learning is essential for animal survival under changing environments. Even in its simplest form, learning involves interactions between a handful of neuronal circuits, hundreds of neurons and many thousand synapses. In this review I will… read more here.
Keywords: acoustic startle; neuroplasticity acoustic; habituation; reflex larval ... See more keywords
Respiratory modulation of intensity ratings and psychomotor response times to acoustic startle stimuli
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience letters"
DOI: 10.1016/j.neulet.2019.134388
Abstract: Respiratory interoception may play an important role in the perception of respiratory symptoms in pulmonary diseases. As the respiratory cycle affects startle eye blink responses, startle modulation may be used to assess visceral-afferent signals from… read more here.
Keywords: respiratory modulation; modulation; acoustic startle; startle stimuli ... See more keywords
Blast Exposure Impairs Sensory Gating: Evidence from Measures of Acoustic Startle and Auditory Event-Related Potentials
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neurotrauma"
DOI: 10.1089/neu.2018.5801
Abstract: Abstract Many military service members and veterans who have been exposed to high-intensity blast waves experience traumatic brain injury (TBI), resulting in chronic auditory deficits despite normal hearing sensitivity. The current study sought to examine… read more here.
Keywords: blast exposure; habituation; acoustic startle; sensory gating ... See more keywords
Acoustic startle stimuli inhibit pain but do not alter nociceptive flexion reflexes to sural nerve stimulation.
Sign Up to like & getrecommendations! Published in 2021 at "Psychophysiology"
DOI: 10.1111/psyp.13757
Abstract: Acoustic startle stimuli inhibit pain, but whether this is due to a cross-modal inhibitory process or some other mechanism is uncertain. To investigate this, electrical stimulation of the sural nerve either preceded or followed an… read more here.
Keywords: acoustic startle; startle stimulus; startle stimuli; startle ... See more keywords
Comprehensive Behavioral Analysis of Opsin 3 (Encephalopsin)-Deficient Mice Identifies Role in Modulation of Acoustic Startle Reflex
Sign Up to like & getrecommendations! Published in 2022 at "eNeuro"
DOI: 10.1523/eneuro.0202-22.2022
Abstract: Abstract Opsin-3 (Opn3, encephalopsin) was the first nonvisual opsin gene discovered in mammals. Since then, several Opn3 functions have been described, and in two cases (adipose tissue, smooth muscle) light sensing activity is implicated. In… read more here.
Keywords: opsin; role; deficient mice; acoustic startle ... See more keywords
The acoustic startle reflex as a tool for assessment of odor environment effects on affective states in laboratory mice.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental animals"
DOI: 10.1538/expanim.20-0111
Abstract: Apart from self and conspecific odors, odors from other species also influence the affective states in laboratory mice (Musmusculus musculus) in their home cages and during experimental procedures, possibly inducing confusion and inconsistency in experimental… read more here.
Keywords: acoustic startle; states laboratory; laboratory mice; odor ... See more keywords
Prepulse inhibition of the acoustic startle reflex impairment by 5-HT2A receptor activation in the inferior colliculus is prevented by GABAA receptor blockade in the pedunculopontine tegmental nucleus
Sign Up to like & getrecommendations! Published in 2023 at "Behavioural Brain Research"
DOI: 10.2139/ssrn.4309315
Abstract: The relationship between serotonin dysfunction and schizophrenia commenced with the discovery of the effects of lysergic acid diethylamide (LSD) that has high affinity for 5-HT2A receptors. Activation of these receptors produces perceptual and behavioural changes… read more here.
Keywords: ht2a; doi; inferior colliculus; prepulse inhibition ... See more keywords
Quantifying the Acoustic Startle Response in Mice Using Standard Digital Video
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Behavioral Neuroscience"
DOI: 10.3389/fnbeh.2020.00083
Abstract: The startle response is an unconditional reflex, characterized by the rapid contraction of facial and skeletal muscles, to a sudden and intense startling stimulus. It is an especially useful tool in translational research for its… read more here.
Keywords: acoustic startle; response; system; using standard ... See more keywords
Age- and sex-specific effects of maternal separation on the acoustic startle reflex in rats: early baseline enhancement in females and blunted response to ambiguous threat
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Behavioral Neuroscience"
DOI: 10.3389/fnbeh.2022.1023513
Abstract: Early life adversity (ELA) increases the incidence of later-life anxiety disorders. Dysregulated threat processing, including responsivity to ambiguous threats, is an indicator of anxiety disorders and can be influenced by childhood experiences. The acoustic startle… read more here.
Keywords: age sex; threat; acoustic startle; sex specific ... See more keywords