A novel bedside test for ACPA: the CCPoint test is moving the laboratory to the rheumatologist’s office
Sign Up to like & getrecommendations! Published in 2017 at "Immunologic Research"
DOI: 10.1007/s12026-016-8846-2
Abstract: Rheumatoid Arthritis (RA) is an autoimmune destructive joint disease affecting 1 % of the general population. In recent years, the benefits of identifying RA at an early stage and initiating therapy before joint damage occurs have… read more here.
Keywords: test; ccpoint; ccpoint test; acpa ... See more keywords
Analyse chromosomique par puce à ADN (ACPA) en fœtopathologie et diagnostic prénatal : retour d’expérience du service de cytogénétique et biologie cellulaire du CHU de Rennes
Sign Up to like & getrecommendations! Published in 2017 at "Morphologie"
DOI: 10.1016/j.morpho.2017.07.040
Abstract: Nous presentons l’experience du service de cytogenetique et biologie cellulaire du CHU de Rennes concernant les analyses chromosomiques par puce a ADN (ACPA) realisees en fœtopathologie et en diagnostic prenatal entre 2009 et 2016 (1256 ACPA). Au… read more here.
Keywords: biologie cellulaire; cellulaire chu; par puce; acpa ... See more keywords
Cross state-dependency of learning between arachidonylcyclopropylamide (ACPA) and muscimol in the mouse dorsal hippocampus
Sign Up to like & getrecommendations! Published in 2017 at "Pharmacology Biochemistry and Behavior"
DOI: 10.1016/j.pbb.2017.10.005
Abstract: Abstract The aim of the present study was to examine cross state‐dependent learning between ACPA (a selective cannabinoid CB1 receptor agonist) and muscimol (a selective GABAA receptor agonist) in the step‐down inhibitory avoidance learning task.… read more here.
Keywords: administration; acpa; pre test; muscimol ... See more keywords
Number of individual ACPA reactivities in synovial fluid immune complexes, but not serum anti-CCP2 levels, associate with inflammation and joint destruction in rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2017-212627
Abstract: Introduction Individual patients with rheumatoid arthritis (RA) show divergent specific anti-citrullinated protein/peptide antibodies (ACPA) patterns, but hitherto no individual ACPA specificity has consistently been linked to RA pathogenesis. ACPA are also implicated in immune complexes… read more here.
Keywords: acpa reactivities; inflammation; number; acpa ... See more keywords
SAT0060 Response to conventional synthetic dmards differs depending on rheumatoid factor levels in anti-citrullinated positive patients with early rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2017 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2017-eular.5778
Abstract: Background In rheumatoid arthritis (RA), several autoantibody characteristics, including specifities, levels and isotypes, may influence their pathogenic properties and impact on clinical presentation and outcomes of the disease (1, 2). In particular, classical IgM rheumatoid… read more here.
Keywords: acpa positive; response; positive patients; disease ... See more keywords
P001 Mechanisms of bone erosion and pain triggered by antibodies targeting post-translational protein modifications in rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-ewrr2018.28
Abstract: Introduction Pain and bone loss are cardinal features of rheumatoid arthritis (RA), which can be triggered by anti-citrullinated protein antibodies (ACPAs). Objectives We aimed to investigate whether ACPA fine specificities could influence osteoclast (OC) induction… read more here.
Keywords: bone; rheumatoid arthritis; acpa; bone erosion ... See more keywords
Standardisation of ACPA tests: evaluation of a new candidate reference preparation
Sign Up to like & getrecommendations! Published in 2022 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2021-221849
Abstract: Introduction Commercial assays measuring antibodies to citrullinated protein/peptide (ACPA) show poor quantitative agreement. The diagnostic industry has never adopted the International Union of Immunological Societies-Centers for Disease Control and Prevention (IUIS-CDC) ACPA reference standard. Recently,… read more here.
Keywords: iuis cdc; reference; nibsc 204; acpa ... See more keywords
POS0603 ANALYSIS OF FACTORS ASSOCIATED WITH THE EFFECTIVENESS OF ABATACEPT IN THE ORIGAMI STUDY
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DOI: 10.1136/annrheumdis-2021-eular.1028
Abstract: The ORIGAMI study is a multicenter, observational study to evaluate the effectiveness, safety, and patient-reported outcomes of abatacept (ABA) in Japanese patients with csDMARD-resistant, Simplified Disease Activity Index (SDAI)-moderate, biologic-naïve rheumatoid arthritis (RA). ABA has… read more here.
Keywords: ltd; acpa; study; disease ... See more keywords