Abstract P6-03-21: Identification of mechanisms driving acquired chemoresistance in preclinical breast cancer models of taxane resistance
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DOI: 10.1158/1538-7445.sabcs19-p6-03-21
Abstract: Background: Taxanes are an established part of the treatment regime for early and metastatic breast cancer. However acquired chemoresistance remains a major factor in therapeutic failure in these patients. Treatment options thereafter are limited. It… read more here.
Keywords: cancer; acquired chemoresistance; taxane resistance; breast cancer ... See more keywords
ALDH1A3 upregulation and spontaneous metastasis formation is associated with acquired chemoresistance in colorectal cancer cells
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DOI: 10.1186/s12885-018-4758-y
Abstract: BackgroundEfficiency of colorectal carcinoma treatment by chemotherapy is diminished as the resistance develops over time in patients. The same holds true for 5-fluorouracil, the drug used in first line chemotherapy of colorectal carcinoma.MethodsChemoresistant derivative of… read more here.
Keywords: chemoresistance colorectal; chemoresistance; colorectal cancer; resistance ... See more keywords