Characterization and Clinical Association of Autoantibodies Against Perilipin 1 in Patients with Acquired Generalized Lipodystrophy.
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DOI: 10.2337/db21-1086
Abstract: Acquired generalized lipodystrophy (AGL) is a rare condition characterized by massive loss of adipose tissue through the body, causing severe metabolic complications. Autoimmune destruction of adipocytes is strongly suspected based on the frequent association of… read more here.
Keywords: autoantibodies perilipin; anti plin1; acquired generalized; plin1 ... See more keywords
Autoantibodies to Perilipin-1 Define a Subset of Acquired Generalized Lipodystrophy.
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DOI: 10.2337/db21-1172
Abstract: Acquired lipodystrophy is often characterized as an idiopathic subtype of lipodystrophy. Despite suspicion of an immune-mediated pathology, biomarkers such as autoantibodies are generally lacking. Here, we used an unbiased proteome-wide screening approach to identify autoantibodies… read more here.
Keywords: plin1 autoantibodies; acquired generalized; lipodystrophy; generalized lipodystrophy ... See more keywords