Treatment of acquired Thrombotic Thrombocytopenic Purpura in the U.S. remains heterogeneous: Current and future points of clinical equipoise
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Apheresis"
DOI: 10.1002/jca.21600
Abstract: The purpose of this survey was to describe current practices in the U.S. for treatment of acquired Thrombotic Thrombocytopenic Purpura (TTP), compare these with prior U.S. and current Canadian practices, and identify areas of clinical… read more here.
Keywords: acquired thrombotic; thrombotic thrombocytopenic; treatment acquired; clinical equipoise ... See more keywords
Benchmarking the centralized urgent plasma exchange service for patients admitted with a diagnosis of suspected acquired thrombotic thrombocytopenic purpura at a large healthcare system
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Apheresis"
DOI: 10.1002/jca.21916
Abstract: Consensus guidelines recommend that therapeutic plasma exchange (TPE) should be started within 4 to 8 hours after the diagnosis of suspected acquired thrombotic thrombocytopenic purpura (aTTP). This study aimed to audit the steps from diagnosis… read more here.
Keywords: diagnosis suspected; plasma exchange; acquired thrombotic; suspected acquired ... See more keywords
Acquired Thrombotic Thrombocytopenic Purpura in a 5-Year-old Child With Wiskott-Aldrich Syndrome
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Pediatric Hematology/Oncology"
DOI: 10.1097/mph.0000000000002150
Abstract: Thrombocytopenia is often seen as a laboratory finding during childhood. A supposed idiopathic thrombocytopenic purpura patient who was later diagnosed as Wiskott-Aldrich syndrome (WAS) and developed acquired thrombotic thrombocytopenic purpura (aTTP). Although autoimmune manifestations in… read more here.
Keywords: acquired thrombotic; thrombocytopenic purpura; aldrich syndrome; year ... See more keywords
Clinical presentation and management of acquired thrombotic thrombocytopenic purpura: A case series of 55 patients
Sign Up to like & getrecommendations! Published in 2020 at "Therapeutic Apheresis and Dialysis"
DOI: 10.1111/1744-9987.13502
Abstract: The aim of this study was to explore the clinical characteristics and treatment of acquired thrombotic thrombocytopenic purpura (TTP). The clinical manifestations, laboratory findings, differential diagnoses, therapeutic methods, and prognosis of 55 patients with acquired… read more here.
Keywords: acquired thrombotic; thrombocytopenic purpura; thrombotic thrombocytopenic; plasma exchange ... See more keywords
Caplacizumab reduces the frequency of major thromboembolic events, exacerbations and death in patients with acquired thrombotic thrombocytopenic purpura
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Thrombosis and Haemostasis"
DOI: 10.1111/jth.13716
Abstract: Essentials Acquired thrombotic thrombocytopenic purpura (aTTP) is linked with significant morbidity/mortality. Caplacizumab's effect on major thromboembolic (TE) events, exacerbations and death was studied. Fewer caplacizumab‐treated patients had a major TE event, an exacerbation, or died… read more here.
Keywords: thromboembolic events; events exacerbations; acquired thrombotic; thrombotic thrombocytopenic ... See more keywords
Real-world data confirm the effectiveness of caplacizumab in acquired thrombotic thrombocytopenic purpura.
Sign Up to like & getrecommendations! Published in 2020 at "Blood advances"
DOI: 10.1182/bloodadvances.2020001973
Abstract: Acquired thrombotic thrombocytopenic purpura (aTTP) is a rare but life-threatening condition. In 2018, the nanobody caplacizumab was approved for the treatment of adults experiencing an acute episode of aTTP, in conjunction with plasma exchange (PEX)… read more here.
Keywords: real world; treatment; acquired thrombotic; caplacizumab ... See more keywords
The Challenges in Diagnosis and Management of Acquired Thrombotic Thrombocytopenic Purpura: A Consensus Report from Three Gulf Countries
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DOI: 10.5001/omj.2022.32
Abstract: Acquired thrombotic thrombocytopenic purpura (aTTP) is a rare hematological emergency that is characterized by microangiopathic hemolytic anemia (MHA), thrombocytopenia, fever, and multiorgan failure due to autoimmune-mediated deficiency in ADAMTS-13 activity. Currently plasma exchange, with or… read more here.
Keywords: consensus; consensus report; acquired thrombotic; thrombotic thrombocytopenic ... See more keywords