M3 but not M4 muscarinic receptors in the rostromedial tegmental nucleus are involved in the acquisition of morphine-induced conditioned place preference.
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DOI: 10.1016/j.ejphar.2020.173274
Abstract: Opioids strongly inhibit GABAergic neurons in the rostromedial tegmental nucleus (RMTg) that expresses μ-opioid receptors to induce rewarding and psychomotor effects. M3 and M4 muscarinic receptors are co-localized with μ-opioid receptors at these GABAergic neurons.… read more here.
Keywords: morphine induced; morphine; acquisition morphine; muscarinic receptors ... See more keywords