Dopamine transporter gene expression within the nucleus accumbens plays important role in the acquisition and reinstatement of ethanol-seeking behavior in mice
Sign Up to like & getrecommendations! Published in 2020 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2020.112475
Abstract: Alcoholism and alcohol use disorders are chronically relapsing conditions which is a major problem in treating alcohol addiction. In a previous study we showed that the dopamine transporter (DAT) is implicated in voluntary intake and… read more here.
Keywords: acquisition reinstatement; etoh cpp; role; dat ... See more keywords
Mirtazapine impairs acquisition and reinstatement of cocaine‐induced place preference in rats
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DOI: 10.1016/j.ejphar.2017.12.033
Abstract: ABSTRACT Exposure to cues previously associated with drug use and the environment can trigger intense craving and drug‐seeking, often leading to relapse in individuals with substance use disorders. Several studies suggest that the decrease in… read more here.
Keywords: cocaine; preference; reinstatement cocaine; acquisition reinstatement ... See more keywords
Glutamate receptor-interacting protein 1 in D1- and D2-dopamine receptor-expressing medium spiny neurons differentially regulates cocaine acquisition, reinstatement, and associated spine plasticity
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2022.979078
Abstract: Background The nucleus accumbens (NAc) is involved in the expression of cocaine addictive phenotypes, including acquisition, extinction, and reinstatement. In the NAc, D1-medium spiny neurons (MSNs) encode cocaine reward, whereas D2-MSNs encode aversive responses in… read more here.
Keywords: reinstatement; acquisition reinstatement; grip1; cocaine acquisition ... See more keywords