Response to immune checkpoint inhibitors in acral melanoma: A nationwide cohort study.
Sign Up to like & getrecommendations! Published in 2022 at "European journal of cancer"
DOI: 10.1016/j.ejca.2022.02.026
Abstract: BACKGROUND Recent reports suggest the limited efficacy of immune checkpoints inhibitors in advanced acral melanoma (AM). This study aims to investigate the clinical outcomes of immune checkpoint inhibitors in patients with stage III and IV AM… read more here.
Keywords: response; immune checkpoint; study; cohort ... See more keywords
Lymphatic invasion in acral and non-acral melanoma: a comparative, clinicoprognostic study of primary cutaneous melanoma according to tumour site.
Sign Up to like & getrecommendations! Published in 2020 at "Pathology"
DOI: 10.1016/j.pathol.2020.06.011
Abstract: There have been limited studies comparing the clinical significance of lymphatic invasion in melanoma according to tumour site. The objective of this study was to evaluate the impact of lymphatic invasion on the clinicoprognostic features… read more here.
Keywords: melanoma; lymphatic invasion; acral melanoma; non acral ... See more keywords
Acral melanoma: a retrospective cohort from the Brazilian National Cancer Institute (INCA)
Sign Up to like & getrecommendations! Published in 2018 at "Melanoma Research"
DOI: 10.1097/cmr.0000000000000476
Abstract: Acral melanoma (AM) is a rare subtype of melanoma arising on the palms, soles and subungual areas. In the Brazilian and Latin American populations, the sociodemographic and clinical-pathologic features of AM are unclear. AM tends… read more here.
Keywords: melanoma; cohort brazilian; retrospective cohort; acral melanoma ... See more keywords
Acral melanoma foot lesions. Part 1: epidemiology, aetiology, and molecular pathology
Sign Up to like & getrecommendations! Published in 2017 at "Clinical and Experimental Dermatology"
DOI: 10.1111/ced.13243
Abstract: Acral melanoma (AM) is a rare subtype of cutaneous malignant melanoma (MM) found on acral skin, primarily on the soles of the feet. Although rare, it is the most common subtype of MM found in… read more here.
Keywords: part; acral melanoma; aetiology molecular; pathology ... See more keywords
Novel LRRFIP2‐RAF1 fusion identified in an acral melanoma: A review of the literature on melanocytic proliferations with RAF1 fusions and the potential therapeutic implications
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cutaneous Pathology"
DOI: 10.1111/cup.13817
Abstract: A small subset of cutaneous melanomas harbor oncogenic gene fusions, which could potentially serve as therapeutic targets for patients with advanced disease as novel therapies are developed. Fusions involving RAF1 are exceedingly rare in melanocytic… read more here.
Keywords: melanoma; raf1; acral melanoma; raf1 fusion ... See more keywords
Adjuvant PD‐1 inhibitor versus high‐dose interferon α‐2b for Chinese patients with cutaneous and acral melanoma: A retrospective cohort analysis
Sign Up to like & getrecommendations! Published in 2021 at "Dermatologic Therapy"
DOI: 10.1111/dth.15067
Abstract: The clinical efficacy of PD‐1 inhibitors as an adjuvant treatment for Asian melanoma patients has not yet been determined. This retrospective study analyzed the clinical data of 90 Chinese patients with completely resected, stage III… read more here.
Keywords: melanoma; cutaneous acral; acral melanoma; adjuvant inhibitor ... See more keywords
Progression of untreated gastric and pulmonary metastasis in a patient with resected acral melanoma
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Case Reports"
DOI: 10.1136/bcr-2021-247683
Abstract: We report a man in his 80s who presents with epigastric abdominal pain and fatigue for 2 weeks. His medical history was significant for left toe acral melanoma (excised 6 years prior) and a lung mass, further… read more here.
Keywords: progression untreated; pulmonary metastasis; acral melanoma; melanoma ... See more keywords
Efficacy of anti-PD-1 and ipilimumab alone or in combination in acral melanoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal for Immunotherapy of Cancer"
DOI: 10.1136/jitc-2022-004668
Abstract: Background Acral melanoma is a rare melanoma subtype with poor prognosis. Importantly, these patients were not identified as a specific subgroup in the landmark melanoma trials involving ipilimumab and the anti-programmed cell death protein-1 (PD-1)… read more here.
Keywords: efficacy; anti ipilimumab; acral melanoma; melanoma ... See more keywords
Integrative Genomic Profiling Uncovers Therapeutic Targets of Acral Melanoma in Asian Populations
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Cancer Research"
DOI: 10.1158/1078-0432.ccr-21-3344
Abstract: Abstract Purpose: Acral melanoma is the major subtype of melanoma seen in Asian patients with melanoma and is featured by its insidious onset and poor prognosis. The genomic study that elucidates driving mutational events is… read more here.
Keywords: melanoma; melanoma asian; acral melanoma; asian populations ... See more keywords
Clinicopathological analysis of acral melanoma in a single center: a study of 45 cases.
Sign Up to like & getrecommendations! Published in 2020 at "Revista da Associacao Medica Brasileira"
DOI: 10.1590/1806-9282.66.10.1391
Abstract: OBJECTIVE The relationship between the clinicopathological and sociodemographics characteristics of acral melanomas diagnosed at the Hospital do Servidor Público Estadual de São Paulo was analyzed and traced between 1997 and 2016. METHODS An observational, descriptive,… read more here.
Keywords: melanoma single; acral melanoma; study; analysis acral ... See more keywords
Cross-sectional study of acral melanoma awareness in a group of South African final phase medical students.
Sign Up to like & getrecommendations! Published in 2022 at "Indian journal of dermatology, venereology and leprology"
DOI: 10.25259/ijdvl_460_2021
Abstract: BACKGROUND Acral melanoma refers to melanoma arising on the palms, soles and nail unit, which are sun-protected areas and ultraviolet exposure is not a risk factor. Acral melanoma is associated with a poorer prognosis than… read more here.
Keywords: dermatology; south african; study; melanoma ... See more keywords