Acridine/Acridone–Carborane Conjugates as Strong DNA‐Binding Agents with Anticancer Potential
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DOI: 10.1002/cmdc.202200666
Abstract: Synthesis of acridine derivatives that act as DNA‐targeting anticancer agents is an evolving field and has resulted in the introduction of several drugs into clinical trials. Carboranes can be of importance in designing biologically active… read more here.
Keywords: dna; acridine; acridone carborane; dna binding ... See more keywords
Modular Synthetic Routes to Fluorine-Containing Halogenated Phenazine and Acridine Agents That Induce Rapid Iron Starvation in Methicillin-Resistant Staphylococcus aureus Biofilms.
Sign Up to like & getrecommendations! Published in 2022 at "ACS infectious diseases"
DOI: 10.1021/acsinfecdis.1c00402
Abstract: During infection, bacteria use an arsenal of resistance mechanisms to negate antibiotic therapies. In addition, pathogenic bacteria form surface-attached biofilms bearing enriched populations of metabolically dormant persister cells. Bacteria develop resistance in response to antibiotic… read more here.
Keywords: iron; staphylococcus; acridine; modular synthetic ... See more keywords
A pH-responsive molecular capsule with an acridine shell: catch and release of large hydrophobic compounds.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical communications"
DOI: 10.1039/c6cc09094j
Abstract: Unlike common polyaromatic hydrocarbons, acridine is a characteristic compound bearing both π-stackable large surfaces and a protonable nitrogen atom. Here we report the first synthesis of a supramolecular capsule with multiple acridine panels. In water,… read more here.
Keywords: capsule; hydrophobic compounds; large hydrophobic; molecular capsule ... See more keywords
An unexpected dual-response pH probe based on acridine
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DOI: 10.1039/c8ra07283c
Abstract: A new pH fluorescent probe 2,8-bis(acridin-9-ylethynyl)-6H,12H-5,11-methanodibenzo[b,f][1,5]diazocine (TBN), which has two acridine moieties attached to Troger's base, is a useful fluorescent probe for monitoring extreme acidic and alkaline pH. TBN displays an excellent pH dependent behavior… read more here.
Keywords: fluorescent probe; probe; dual response; acridine ... See more keywords
Co-immobilized bienzyme of horseradish peroxidase and glucose oxidase on dopamine-modified cellulose–chitosan composite beads as a high-efficiency biocatalyst for degradation of acridine
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DOI: 10.1039/d2ra04091c
Abstract: Co-immobilized bienzyme biocatalysts are attracting increasing interest in the field of wastewater treatment due to their widespread application. In this study, we successfully prepared a co-immobilized bienzyme biocatalyst by immobilizing horseradish peroxidase (HRP) and glucose… read more here.
Keywords: acridine; bienzyme biocatalyst; immobilized bienzyme; biocatalyst ... See more keywords
Zn2+/Cd2+ optical discrimination by fluorescent acridine-based bis-macrocylic receptors
Sign Up to like & getrecommendations! Published in 2017 at "Supramolecular Chemistry"
DOI: 10.1080/10610278.2017.1387262
Abstract: Abstract A new acridine-based fluorescent chemosensor, L2, featuring two sulfurated macrocyclic units has been synthesised. Proton and metal binding properties of L2 have been studied in H2O/CH3CN (1:1 v/v) by potentiometric and spectrophotometric measurements and… read more here.
Keywords: optical discrimination; discrimination fluorescent; cd2 optical; acridine based ... See more keywords
Molecular Engineering of Peripheral Substitutions to Construct Efficient Acridine Core-Based Hole Transport Materials for Perovskite Solar Cells.
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DOI: 10.2139/ssrn.4145274
Abstract: The development of highly efficient hole transport materials (HTMs) for perovskite solar cells (PSCs) has been a hot research topic. Acridine and its derivatives are gradually utilized as new blocks for optoelectronic applications, which stems… read more here.
Keywords: transport materials; core; acridine; solar cells ... See more keywords
DNA INTERCALATING ABILITY OF FOUR ACRIDINE-N-OXYDES DERIVATIVES INVESTIGATED BY SPECTRAL AND ELECTROCHEMICAL TECHNIQUES
Sign Up to like & getrecommendations! Published in 2018 at "Farmacia"
DOI: 10.31925/farmacia.2018.4.19
Abstract: Acridines belong to one of the most frequently studied class of compounds due to their numerous physico-chemical properties and their biological action. Thus, the use of acridines as antitumor, antibacterial, antiviral, antimalarial and antinociceptive agents… read more here.
Keywords: dna intercalating; four acridine; acridine; intercalating ability ... See more keywords