Correlation of polyamines, acrolein-conjugated lysine and polyamine metabolic enzyme levels with age in human liver
Sign Up to like & getrecommendations! Published in 2020 at "Heliyon"
DOI: 10.1016/j.heliyon.2020.e05031
Abstract: The polyamines spermidine, spermine and putrescine are essential for normal cellular functions. The contents of polyamines in tissue decreased in aged mice compared to young mice. In this study, the polyamine contents and their metabolic… read more here.
Keywords: conjugated lysine; acrolein conjugated; age; polyamine ... See more keywords
Acrolein-conjugated proteomics in brains of adult C57BL/6 mice chronically exposed to acrolein and aged APP/PS1 transgenic AD mice.
Sign Up to like & getrecommendations! Published in 2021 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2021.03.001
Abstract: Acrolein is a universal contaminant with high nucleophilicity in environment and also an endogenous product from lipid peroxidation or polyamine metabolism. Acrolein can react with nucleophilic amino acids, such as cysteines, lysines and histidines via… read more here.
Keywords: acrolein conjugated; brains adult; proteomics brains; aged app ... See more keywords