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   Articles with "acromegaly" as a keyword



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Metabolic profiling of acromegaly using a GC–MS-based nontargeted metabolomic approach

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recommendations! Published in 2019 at "Endocrine"

DOI: 10.1007/s12020-019-02143-0

Abstract: Purpose Acromegaly is a rare disease caused by chronic hypersecretion of growth hormone, which leads to multiple comorbidities and reduced life expectancy. The objective of this study was to characterize the serum metabolic profiles of… read more here.

Keywords: acromegaly; glyceric acid; normal controls; acid ... See more keywords
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A single-center experience of transsphenoidal endoscopic surgery for acromegaly in 73 patients: results and predictive factors for remission.

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recommendations! Published in 2021 at "British journal of neurosurgery"

DOI: 10.1080/02688697.2021.1947977

Abstract: BACKGROUND Transsphenoidal endoscopic surgery is the first-line treatment for growth hormone-secreting adenomas. OBJECTIVE To analyse the results of the transsphenoidal endoscopic approach for acromegaly and to determine the predictive factors of remission. METHODS A single-centre… read more here.

Keywords: endoscopic surgery; surgery; transsphenoidal endoscopic; remission ... See more keywords
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Efficacy and Safety of CyberKnife Stereotactic Radiosurgery in Acromegaly

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recommendations! Published in 2021 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noab195.035

Abstract: Objective: Active acromegaly is associated with increased mortality. While surgery is the mainstay of treatment, it is not always curative. In selected cases, CyberKnife stereotactic radiosurgery (CK SRS) can be used as adjuvant treatment in… read more here.

Keywords: efficacy safety; treatment; acromegaly; cyberknife stereotactic ... See more keywords
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Petrified ears due to auricular ossification: an underreported clinical sign in acromegaly

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recommendations! Published in 2022 at "BMJ Case Reports"

DOI: 10.1136/bcr-2021-247186

Abstract: © BMJ Publishing Group Limited 2022. No commercial reuse. See rights and permissions. Published by BMJ. DESCRIPTION Acromegaly due to growth hormone (GH) secreting pituitary macroadenoma (Hardy II A, KNOSP 3) had been diagnosed in… read more here.

Keywords: ossification; petrified ears; auricular ossification; acromegaly ... See more keywords
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Increased ATP-synthesis might counteract hepatic lipid accumulation in acromegaly.

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recommendations! Published in 2020 at "JCI insight"

DOI: 10.1172/jci.insight.134638

Abstract: Patients with active acromegaly (ACRO) exhibit low hepatocellular lipids (HCL) despite pronounced insulin resistance (IR). This contrasts the strong association of IR with non-alcoholic fatty liver disease in the general population. Since low HCL in… read more here.

Keywords: lipid accumulation; acromegaly; atp synthesis; mitochondrial activity ... See more keywords
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Long-term Outcome of Body Composition, Ectopic Lipid, and Insulin Resistance Changes With Surgical Treatment of Acromegaly

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recommendations! Published in 2023 at "Journal of the Endocrine Society"

DOI: 10.1210/jendso/bvad028

Abstract: Abstract Context Acromegaly presents a unique pattern of lower adiposity and insulin resistance in active disease but reduction in insulin resistance despite a rise in adiposity after surgery. Depot-specific adipose tissue masses and ectopic lipid… read more here.

Keywords: long term; insulin resistance; resistance; acromegaly ... See more keywords
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Pegvisomant and Pasireotide LAR as second line therapy in acromegaly: Clinical effectiveness and predictors of response.

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recommendations! Published in 2020 at "European journal of endocrinology"

DOI: 10.1530/eje-20-0767

Abstract: BACKGROUND The treatment of acromegaly resistant to first generation somatostatin receptor ligands (SRLs) is often difficult. Pegvisomant and Pasireotide LAR are mostly used in these subset of patients, as second line therapies. Choice of the… read more here.

Keywords: pasireotide lar; acromegaly; pegvisomant pasireotide; second line ... See more keywords
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Patient's point of view on the diagnosis, treatment, and follow-up in acromegaly: single-center study from a tertiary center.

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recommendations! Published in 2022 at "Revista da Associacao Medica Brasileira"

DOI: 10.1590/1806-9282.20211186

Abstract: OBJECTIVE We aimed to evaluate the awareness and perspectives of acromegaly patients in the diagnosis and treatment processes and to evaluate basic clinical and demographic features. METHODS This cross-sectional study was conducted at the Endocrinology… read more here.

Keywords: diagnosis; diagnosis treatment; acromegaly; center ... See more keywords
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Subclinical Ventricular Dysfunction in Long-Term Acromegaly Assessed by Speckle-Tracking Echocardiography

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recommendations! Published in 2022 at "Frontiers in Endocrinology"

DOI: 10.3389/fendo.2022.812964

Abstract: Introduction Symptomatic heart disease may be present in patients with advanced-stage acromegaly. However, earlier assessment of subclinical ventricular systolic dysfunction can be accomplished through speckle-tracking echocardiography (STE) for the study of myocardial strain. The few… read more here.

Keywords: speckle tracking; acromegaly; subclinical ventricular; strain ... See more keywords
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Acromegaly Caused by Ectopic Growth Hormone Releasing Hormone Secretion: A Review

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recommendations! Published in 2022 at "Frontiers in Endocrinology"

DOI: 10.3389/fendo.2022.867965

Abstract: Introduction Ectopic acromegaly is a rare condition caused most frequently by growth hormone releasing hormone (GHRH) secretion from neuroendocrine tumors. The diagnosis is often difficult to establish as its main symptoms do not differ from… read more here.

Keywords: hormone; ectopic acromegaly; acromegaly; growth hormone ... See more keywords
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The acromegaly lipodystrophy

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recommendations! Published in 2022 at "Frontiers in Endocrinology"

DOI: 10.3389/fendo.2022.933039

Abstract: Growth hormone (GH) and insulin-like growth factor 1 (IGF-1) are essential to normal growth, metabolism, and body composition, but in acromegaly, excesses of these hormones strikingly alter them. In recent years, the use of modern… read more here.

Keywords: acromegaly lipodystrophy; insulin resistance; acromegaly; adipose tissue ... See more keywords