Genetic effects on gene expression across human tissues
Sign Up to like & getrecommendations! Published in 2017 at "Nature"
DOI: 10.1038/nature24277
Abstract: Characterization of the molecular function of the human genome and its variation across individuals is essential for identifying the cellular mechanisms that underlie human genetic traits and diseases. The Genotype-Tissue Expression (GTEx) project aims to… read more here.
Keywords: genetic effects; effects gene; gene expression; expression ... See more keywords
Corrigendum: Landscape of X chromosome inactivation across human tissues
Sign Up to like & getrecommendations! Published in 2018 at "Nature"
DOI: 10.1038/nature25993
Abstract: This corrects the article DOI: 10.1038/nature24265 read more here.
Keywords: landscape chromosome; human tissues; inactivation across; corrigendum landscape ... See more keywords
Genome maps across 26 human populations reveal population-specific patterns of structural variation
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-08992-7
Abstract: Large structural variants (SVs) in the human genome are difficult to detect and study by conventional sequencing technologies. With long-range genome analysis platforms, such as optical mapping, one can identify large SVs (>2 kb) across the… read more here.
Keywords: large svs; genome maps; maps across; across human ... See more keywords
Niosomal formulation of hydroxytyrosol, a polyphenolic antioxidant, for enhancing transdermal delivery across human cadaver skin
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutical Development and Technology"
DOI: 10.1080/10837450.2022.2025540
Abstract: Abstract Hydroxytyrosol (HT), a naturally occurring polyphenol from the olive plant, is a potent antioxidant, cardioprotective, neuroprotective, and anti-inflammatory agent. Upon oral administration, HT undergoes rapid elimination within minutes and thus limiting its therapeutic utility.… read more here.
Keywords: skin; formulation; transdermal delivery; delivery ... See more keywords
HeRA: an atlas of enhancer RNAs across human tissues
Sign Up to like & getrecommendations! Published in 2021 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkaa940
Abstract: Abstract Enhancer RNA (eRNA) is a type of long non-coding RNA transcribed from DNA enhancer regions. Despite critical roles of eRNA in gene regulation, the expression landscape of eRNAs in normal human tissue remains unexplored.… read more here.
Keywords: tissues hera; human tissues; expression; across human ... See more keywords
The Aging Slow Wave: A Shifting Amalgam of Distinct Slow Wave and Spindle Coupling Subtypes Define Slow Wave Sleep Across the Human Lifespan.
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DOI: 10.1093/sleep/zsab125
Abstract: STUDY OBJECTIVES Slow wave and spindle coupling supports memory consolidation, and loss of coupling is linked with cognitive decline and neurodegeneration. Coupling is proposed to be a possible biomarker of neurological disease, yet little is… read more here.
Keywords: human lifespan; wave spindle; wave; spindle coupling ... See more keywords
Mapping cell types across human tissues.
Sign Up to like & getrecommendations! Published in 2022 at "Science"
DOI: 10.1126/science.abq2116
Abstract: Single-cell analyses reveal tissue-agnostic features and tissue-specific cell states. read more here.
Keywords: cell; types across; cell types; mapping cell ... See more keywords
The Strength of Social Norms Across Human Groups
Sign Up to like & getrecommendations! Published in 2017 at "Perspectives on Psychological Science"
DOI: 10.1177/1745691617708631
Abstract: Social norms are a defining feature of human psychology, yet our understanding of them is still underdeveloped. In this article, we present our own cross-cultural research program on tightness-looseness (TL)—which draws on field, experimental, computational,… read more here.
Keywords: human groups; social norms; norms across; across human ... See more keywords
Biogeography and environmental conditions shape bacteriophage-bacteria networks across the human microbiome
Sign Up to like & getrecommendations! Published in 2018 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1006099
Abstract: Viruses and bacteria are critical components of the human microbiome and play important roles in health and disease. Most previous work has relied on studying bacteria and viruses independently, thereby reducing them to two separate… read more here.
Keywords: network; human microbiome; phage; networks across ... See more keywords
Pan-Cancer Analysis of the Characteristics of LY96 in Prognosis and Immunotherapy Across Human Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.837393
Abstract: Lymphocyte antigen 96 (LY96) is implicated in tumorigenesis by modulating host immunity. However, an integrated pan-cancer analysis of LY96 in prognosis and immunotherapy across human cancers is still lacking. Therefore, we analyzed the LY96 expression… read more here.
Keywords: across human; immunotherapy; pan cancer; ly96 prognosis ... See more keywords