Normalizing Polydiacetylene Colorimetric Assays of Vesicle Binding Across Lipid Systems.
Sign Up to like & getrecommendations! Published in 2020 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2020.113864
Abstract: Mixed polydiacetylene (PDA) lipid vesicles mimic cell membranes and exhibit a colorimetric response induced by mechanical stress, which can be used to determine the affinity of proteins or molecules for lipid membranes. Due to a… read more here.
Keywords: polydiacetylene colorimetric; normalizing polydiacetylene; colorimetric assays; assays vesicle ... See more keywords
pH-Dependent transport of amino acids across lipid bilayers by simple monotopic anion carriers
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DOI: 10.1039/d2sc04346g
Abstract: The transport of amino acids across lipid membranes is vital for the proper functioning of every living cell. In spite of that, examples of synthetic transporters that can facilitate amino acid transport are rare. This… read more here.
Keywords: amino acids; across lipid; transport; amino acid ... See more keywords
Label-free quantification of passive membrane permeability of cyclic peptides across lipid bilayers: penetration speed of cyclosporin A across lipid bilayers
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DOI: 10.1039/d2sc05785a
Abstract: Cyclic peptides that passively penetrate cell membranes are under active investigation in drug discovery research. PAMPA (Parallel Artificial Membrane Permeability Assay) and Caco-2 assay are mainly used for permeability measurements in these studies. However, permeability… read more here.
Keywords: cyclic peptides; across lipid; membrane permeability; permeability ... See more keywords
Each side chain of cyclosporin A is not essential for high passive permeability across lipid bilayers
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DOI: 10.1039/d3ra01358h
Abstract: We compared the passive permeability of cyclosporin A (CsA) derivatives with side chain deletions across lipid bilayers. CsA maintained passive permeability after losing any one of the side chains, which suggests that the propensity of… read more here.
Keywords: side chain; passive permeability; across lipid; high passive ... See more keywords