Bridging across patient subgroups in phase I oncology trials that incorporate animal data
Sign Up to like & getrecommendations! Published in 2021 at "Statistical Methods in Medical Research"
DOI: 10.1177/0962280220986580
Abstract: In this paper, we develop a general Bayesian hierarchical model for bridging across patient subgroups in phase I oncology trials, for which preliminary information about the dose–toxicity relationship can be drawn from animal studies. Parameters… read more here.
Keywords: patient subgroups; phase oncology; bridging across; across patient ... See more keywords