Joint Bounding of Peaks Across Samples Improves Differential Analysis in Mass Spectrometry-Based Metabolomics
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DOI: 10.1021/acs.analchem.6b04719
Abstract: As mass spectrometry-based metabolomics becomes more widely used in biomedical research, it is important to revisit existing data analysis paradigms. Existing data preprocessing efforts have largely focused on methods which start by extracting features separately… read more here.
Keywords: differential analysis; mass spectrometry; analysis; based metabolomics ... See more keywords
Unsupervised Discovery and Comparison of Structural Families Across Multiple Samples in Untargeted Metabolomics
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DOI: 10.1021/acs.analchem.7b01391
Abstract: In untargeted metabolomics approaches, the inability to structurally annotate relevant features and map them to biochemical pathways is hampering the full exploitation of many metabolomics experiments. Furthermore, variable metabolic content across samples result in sparse… read more here.
Keywords: discovery comparison; unsupervised discovery; structural families; untargeted metabolomics ... See more keywords
Construct identification in the neuropsychological battery: What are we measuring?
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DOI: 10.1037/neu0000832.supp
Abstract: OBJECTIVE Major obstacles to data harmonization in neuropsychology include lack of consensus about what constructs and tests are most important and invariant across healthy and clinical populations. This study addressed these challenges using data from… read more here.
Keywords: recognition familiarity; factor; across samples; construct identification ... See more keywords
Metagenomics of infective canaliculitis: The Lacriome paper 3
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DOI: 10.1177/11206721221091646
Abstract: Purpose To study the metagenomics of the microbes isolated from the canaliculus of patients with infective canaliculitis. Methods A prospective study was performed on five consecutive canalicular samples obtained for the metagenomic analysis from the… read more here.
Keywords: lacriome paper; canaliculitis lacriome; across samples; canaliculitis ... See more keywords