Dosing algorithms for vitamin K antagonists across VKORC1 and CYP2C9 genotypes
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DOI: 10.1111/jth.13615
Abstract: Essentials Prospective studies of pharmacogenetic‐guided (PG) coumarin dosing produced varying results. EU‐PACT acenocoumarol and phenprocoumon trials compared PG and non‐PG dosing algorithms. Sub‐analysis of EU‐PACT identified differences between trial arms across VKORC1‐CYP2C9 groups. Adjustment of… read more here.
Keywords: dosing algorithms; vkorc1 cyp2c9; algorithms vitamin; across vkorc1 ... See more keywords