LAUSR

Acrylamide Functional Group Incorporation Improves Drug-like Properties: An Example with EGFR Inhibitors.

Sign Up to like & get
recommendations!
1 Published in 2019 at "ACS medicinal chemistry letters"

DOI: 10.1021/acsmedchemlett.8b00270

Abstract: We demonstrate that the acrylamide group can be used to improve the drug-like properties of potential drug candidates. In the EGFR inhibitor development, both the solubility and membrane permeability properties of compounds 6a and 7,… read more here.

Keywords: acrylamide functional; group; drug; incorporation ... See more keywords