Optimal antiplatelet and anticoagulation strategies in acute coronary syndromes
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DOI: 10.1007/s00059-020-04947-7
Abstract: Antithrombotic therapy has become increasingly challenging due to the thrombotic and bleeding risk of patients presenting with acute coronary syndrome (ACS) today. Contributing factors include increasing age, underlying comorbidities (e.g., renal failure, atrial fibrillation [AF]),… read more here.
Keywords: die; risk; acs; der ... See more keywords
One-Year COMBO Stent Outcomes in Acute Coronary Syndrome: from the COMBO Collaboration
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DOI: 10.1007/s10557-020-07087-6
Abstract: The COMBO biodegradable polymer sirolimus-eluting stent includes endothelial progenitor cell capture (EPC) technology for rapid endothelialization, which may offer advantage in acute coronary syndromes (ACS). We sought to analyze the performance of the COMBO stent… read more here.
Keywords: stemi; combo stent; acs; year ... See more keywords
Prediction of activity cliffs on the basis of images using convolutional neural networks
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DOI: 10.1007/s10822-021-00380-y
Abstract: An activity cliff (AC) is formed by a pair of structurally similar compounds with a large difference in potency. Accordingly, ACs reveal structure–activity relationship (SAR) discontinuity and provide SAR information for compound optimization. Herein, we… read more here.
Keywords: acs; convolutional neural; cnn models; prediction activity ... See more keywords
Guided de-escalation of DAPT in acute coronary syndrome patients undergoing percutaneous coronary intervention with BVS implantation: a post-hoc analysis from the randomized TROPICAL-ACS trial
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Thrombosis and Thrombolysis"
DOI: 10.1007/s11239-019-01811-2
Abstract: To investigate the safety and efficacy of an early platelet function testing (PFT)-guided de-escalation of dual antiplatelet treatment (DAPT) in acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI) with bioresorbable vascular scaffolds (BVS).… read more here.
Keywords: hoc analysis; post hoc; acs; implantation ... See more keywords
The value of psychometric analysis of the advanced trauma life support cognitive test: Outcome of an ACS-Accredited educational institute multisite study.
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DOI: 10.1016/j.amjsurg.2018.07.050
Abstract: BACKGROUND The Advanced Trauma Life Support® (ATLS®) course provides a standard approach to trauma. Participants must pass the ATLS® post-test. We deployed the test online to allow ongoing psychometric item analysis and potential objective refinement.… read more here.
Keywords: life support; acs; analysis; advanced trauma ... See more keywords
Risk of acute coronary syndrome in patients with cervical spondylosis.
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DOI: 10.1016/j.atherosclerosis.2018.02.029
Abstract: BACKGROUND AND AIMS Cervical spondylosis (CS) is reported to be associated with increased sympathetic activity and hypertension. However, the cardiovascular (CV) outcomes of patients with CS are largely unknown. METHODS A national insurance claims dataset… read more here.
Keywords: risk; acs; acute coronary; cervical spondylosis ... See more keywords
Association of plasma CD40L with acute chest syndrome in sickle cell anemia
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DOI: 10.1016/j.cyto.2017.05.017
Abstract: &NA; Platelet activation and platelet‐derived cytokines contribute to the vascular inflammation and increased thrombotic activity known to occur in patients with sickle cell anemia (SCA). CD40 ligand (CD40L), a platelet‐associated pro‐inflammatory molecule that promotes endothelial… read more here.
Keywords: acs; cd40l; cell; platelet ... See more keywords
TCTAP A-013 Trend of Anti-diabetic Treatment Strategy and Influence of Outcomes in Diabetic ACS Patient: Data from Taiwan ACS-DM Registry
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DOI: 10.1016/j.jacc.2018.03.039
Abstract: Patients with acute coronary syndrome (ACS) and diabetes mellitus (DM) received less aggressive treatment and had worse outcomes in Taiwan. We sought to explore whether the current practices of prescribing evidence-based medications for ACS and… read more here.
Keywords: acs; treatment; anti diabetic; 013 trend ... See more keywords
Stent Thrombosis With Dual Antithrombotic Therapy in Atrial Fibrillation-ACS/PCI Trials.
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DOI: 10.1016/j.jacc.2020.01.054
Abstract: There are now 6 randomized controlled trials (RCTs) comparing dual (DAT) versus triple antithrombotic therapy (TAT) in patients with atrial fibrillation (AF) and acute coronary syndrome (ACS) or undergoing percutaneous coronary intervention (PCI) ([1][1]). The… read more here.
Keywords: atrial fibrillation; acs; pci; antithrombotic therapy ... See more keywords
International Prospective Registry of Acute Coronary Syndromes in Patients With COVID-19
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DOI: 10.1016/j.jacc.2021.03.309
Abstract: Background Published data suggest worse outcomes in acute coronary syndrome (ACS) patients and concurrent coronavirus disease 2019 (COVID-19) infection. Mechanisms remain unclear. Objectives The purpose of this study was to report the demographics, angiographic findings,… read more here.
Keywords: acs; acs patients; covid; acute coronary ... See more keywords
Effect of American College of Surgeons Trauma Center Designation on Outcomes: Measurable Benefit at the Extremes of Age and Injury.
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DOI: 10.1016/j.jamcollsurg.2017.04.034
Abstract: BACKGROUND American College of Surgeons (ACS) verification is believed to provide benefits for trauma patients, but is associated with direct costs. STUDY DESIGN We performed a 1-year retrospective review of the National Trauma Data Bank… read more here.
Keywords: non acs; age; acs; american college ... See more keywords