Targeting ACSL1 promotes cardiomyocyte proliferation and cardiac regeneration.
Sign Up to like & getrecommendations! Published in 2022 at "Life sciences"
DOI: 10.1016/j.lfs.2022.120371
Abstract: BACKGROUND Neonatal hearts have considerable regenerative potential within 7 days post birth (P7), but the rate of regeneration is extremely low after P7. Interestingly, lipid metabolism increases dramatically after P7. The similarities in these age profiles… read more here.
Keywords: acsl1; myocardial regeneration; lipid metabolism; cardiac regeneration ... See more keywords
1786-P: ACSL1 Contributes to Thermogenesis and Differentiation of Brown Adipose Tissue
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DOI: 10.2337/db19-1786-p
Abstract: Long chain acyl-CoA synthetases (ACSLs) convert fatty acids (FA) to fatty acyl-CoAs that are utilized for various cellular processes, including triglyceride synthesis, activation of transcription factors, signal transduction, and providing energy sources via oxidation. Among… read more here.
Keywords: bat; acsl1; differentiation; differentiation brown ... See more keywords
Transcriptional analysis of microRNAs related to unsaturated fatty acid synthesis by interfering bovine adipocyte ACSL1 gene
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DOI: 10.3389/fgene.2022.994806
Abstract: Long-chain fatty acyl-CoA synthase 1 (ACSL1) plays a vital role in the synthesis and metabolism of fatty acids. The proportion of highly unsaturated fatty acids in beef not only affects the flavor and improves the… read more here.
Keywords: acid synthesis; acsl1; unsaturated fatty; bovine ... See more keywords
MiR-218-5p Affects Subcutaneous Adipogenesis by Targeting ACSL1, a Novel Candidate for Pig Fat Deposition
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DOI: 10.3390/genes13020260
Abstract: As a centre enzyme in fatty acid activation, acyl-CoA synthetase long-chain family member 1 (ACSL1) plays an important role in body lipid homeostasis. However, the functions of ACSL1 in the subcutaneous adipogenesis of pigs are… read more here.
Keywords: fat deposition; acsl1; mir 218; subcutaneous adipogenesis ... See more keywords