Acyl‐CoA synthetase short‐chain family member 2 (ACSS2) is regulated by SREBP‐1 and plays a role in fatty acid synthesis in caprine mammary epithelial cells
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DOI: 10.1002/jcp.25954
Abstract: Sterol regulatory element binding protein 1 (SREBP‐1) is well‐known as the master regulator of lipogenesis in rodents. Acyl‐CoA synthetase short‐chain family member 2 (ACSS2) plays a key role in lipogenesis by synthesizing acetyl‐CoA from acetate… read more here.
Keywords: fatty acid; lipogenesis; acyl coa; acss2 ... See more keywords
Acetyl-coA Synthetase 2 potentiates macropinocytosis and muscle wasting through metabolic reprogramming in pancreatic cancer.
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DOI: 10.1053/j.gastro.2022.06.058
Abstract: BACKGROUND & AIMS Rapid deconditioning, also called cachexia, and metabolic reprogramming are two hallmarks of pancreatic cancer. ACSS2 is an acetyl-coA synthetase that contributes to lipid synthesis and epigenetic reprogramming. However, the role of ACSS2… read more here.
Keywords: acss2; muscle wasting; pancreatic cancer; metabolic reprogramming ... See more keywords
Abstract 1799: Regulation of epidermal stem cell proliferation and adhesion by ACSS2
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DOI: 10.1158/1538-7445.am2024-1799
Abstract: Acetyl-CoA Synthetase Short-Chain Family Member 2 (ACSS2) is an enzyme that converts acetate into acetyl-CoA, a crucial metabolite required for protein acetylation and lipogenesis. Acetyl-CoA is membrane-impermeable and must be synthesized in the compartment in… read more here.
Keywords: cell; proliferation adhesion; acss2; epidermal stem ... See more keywords
miR-4443 Contained Extracellular Vesicles: A Factor for Endometriosis Progression by PI3K/AKT/ACSS2 Cascade in-vitro
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DOI: 10.2147/ijn.s456594
Abstract: Introduction Endometriosis (EM) is an estrogen-dependent benign gynecologic disease affecting approximately 10% of reproductive-age women with a high recurrence rate, but lacks reliable biomarkers. No previous studies have investigated the possible use of extracellular vesicle… read more here.
Keywords: acss2; endometriosis; mir; pi3k akt ... See more keywords