Acss2/HIF-2 signaling facilitates colon cancer growth and metastasis
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DOI: 10.1371/journal.pone.0282223
Abstract: The microenvironment of solid tumors is characterized by oxygen and glucose deprivation. Acss2/HIF-2 signaling coordinates essential genetic regulators including acetate-dependent acetyl CoA synthetase 2 (Acss2), Creb binding protein (Cbp), Sirtuin 1 (Sirt1), and Hypoxia Inducible… read more here.
Keywords: colon cancer; acss2 hif; hif signaling;