The proline‐rich domain of fission yeast WASp (Wsp1p) interacts with actin filaments and inhibits actin polymerization
Sign Up to like & getrecommendations! Published in 2023 at "FEBS Letters"
DOI: 10.1002/1873-3468.14571
Abstract: Members of the Wiskott–Aldrich Syndrome protein (WASp) family activate Arp2/3 complex (actin‐related proteins 2 and 3 complex) to form actin filament branches. The proline‐rich domain (PRD) of WASp contributes to branching nucleation, and the PRD… read more here.
Keywords: actin filaments; rich domain; proline rich; actin ... See more keywords
Cardiac troponin and tropomyosin bind to F‐actin cooperatively, as revealed by fluorescence microscopy
Sign Up to like & getrecommendations! Published in 2020 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12876
Abstract: In cardiac muscle, binding of troponin (Tn) and tropomyosin (Tpm) to filamentous (F)‐actin forms thin filaments capable of Ca2+‐dependent regulation of contraction. Tpm binds to F‐actin in a head‐to‐tail fashion, while Tn stabilizes these linkages.… read more here.
Keywords: tpm; microscopy; actin; fluorescence microscopy ... See more keywords
Loss of β‐Actin Leads to Accelerated Mineralization and Dysregulation of Osteoblast‐Differentiation Genes during Osteogenic Reprogramming
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Science"
DOI: 10.1002/advs.202002261
Abstract: Abstract Actin plays fundamental roles in both the cytoplasm and the cell nucleus. In the nucleus, β‐actin regulates neuronal reprogramming by consolidating a heterochromatin landscape required for transcription of neuronal gene programs, yet it remains… read more here.
Keywords: actin; actin leads; accelerated mineralization; leads accelerated ... See more keywords
Distinct molecular mechanisms control levels of synaptic F‐actin
Sign Up to like & getrecommendations! Published in 2019 at "Cell Biology International"
DOI: 10.1002/cbin.11226
Abstract: Polymerization of filamentous (F)‐actin at the neuronal synapse plays an important role in neuronal function. However, the regulatory mechanisms controlling the levels of synaptic actin remain incompletely understood. Here, I used established pharmacological blockers to… read more here.
Keywords: actin; distinct molecular; synaptic actin; levels synaptic ... See more keywords
Structural change and degradation of cytoskeleton due to the acrolein conjugation with vimentin and actin during brain infarction
Sign Up to like & getrecommendations! Published in 2020 at "Cytoskeleton"
DOI: 10.1002/cm.21638
Abstract: We have found recently that dendritic spine extension is inhibited through acrolein conjugation with α‐ and β‐tubulin proteins during brain infarction. In this current study, we looked for other acrolein‐conjugated proteins in the 100,000g precipitate… read more here.
Keywords: cytoskeleton; vimentin; actin; brain infarction ... See more keywords
Absence of the Drosophila jump muscle actin Act79B is compensated by up‐regulation of Act88F
Sign Up to like & getrecommendations! Published in 2018 at "Developmental Dynamics"
DOI: 10.1002/dvdy.24616
Abstract: Background: Actins are structural components of the cytoskeleton and muscle, and numerous actin isoforms are found in most organisms. However, many actin isoforms are expressed in distinct patterns allowing each actin to have a specialized… read more here.
Keywords: act88f; jump; actin; muscle ... See more keywords
Jmy regulates oligodendrocyte differentiation via modulation of actin cytoskeleton dynamics
Sign Up to like & getrecommendations! Published in 2018 at "Glia"
DOI: 10.1002/glia.23342
Abstract: During central nervous system development, oligodendrocytes form structurally and functionally distinct actin‐rich protrusions that contact and wrap around axons to assemble myelin sheaths. Establishment of axonal contact is a limiting step in myelination that relies… read more here.
Keywords: oligodendrocyte differentiation; cytoskeleton dynamics; actin; differentiation ... See more keywords
Testin regulates the blood‐testis barrier via disturbing occludin/ZO‐1 association and actin organization
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29541
Abstract: The blood‐testis barrier (BTB) separates the seminiferous epithelium into the apical and basal compartments. The BTB has to operate timely and accurately to ensure the correct migration of germ cells, meanwhile maintaining the immunological barrier.… read more here.
Keywords: barrier; actin; testin rnai; blood testis ... See more keywords
Stage‐dependent localization of F‐actin and Na+/K+‐ATPase in zebrafish embryos detected using optimized cryosectioning immunostaining protocol
Sign Up to like & getrecommendations! Published in 2022 at "Microscopy Research and Technique"
DOI: 10.1002/jemt.24270
Abstract: The increasing use of the zebrafish model in biomedical and (eco)toxicological studies aimed at understanding the function of various proteins highlight the importance of optimizing existing methods to study gene and protein expression and localization… read more here.
Keywords: localization actin; localization; zebrafish cryosections; microscopy ... See more keywords
Using Microfluidics Single Filament Assay to Study Formin Control of Actin Assembly.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8556-2_4
Abstract: Formin is a highly processive motor that offers very unique features to control the elongation of actin filaments. When bound to the filament barbed-end, it enhances the addition of profilin-actin from solution to dramatically accelerate… read more here.
Keywords: actin assembly; actin; study; using microfluidics ... See more keywords
Erratum to: Polar localization of MreB actin is inhibited by anionic phospholipids in the rod-shaped bacterium Escherichia coli
Sign Up to like & getrecommendations! Published in 2017 at "Current Genetics"
DOI: 10.1007/s00294-017-0701-z
Abstract: Bacterial actin MreB is required for the maintenance of cell polarity. MreB is located underneath the cell membrane and mainly localizes at a central cylindrical part of the cell. In addition, it has recently been… read more here.
Keywords: actin; localization mreb; anionic phospholipids; mreb ... See more keywords