Adaptive Response of Actin Bundles under Mechanical Stress
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2017.07.017
Abstract: Actin is one of the main components of the architecture of cells. Actin filaments form different polymer networks with versatile mechanical properties that depend on their spatial organization and the presence of cross-linkers. Here, we… read more here.
Keywords: bundle; adaptive response; bundles mechanical; force ... See more keywords
The C-terminal domain of EFA6A interacts directly with F-actin and assembles F-actin bundles
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-55630-9
Abstract: The Arf6-specific exchange factor EFA6 is involved in the endocytic/recycling pathway for different cargos. In addition EFA6 acts as a powerful actin cytoskeleton organizer, a function required for its role in the establishment of the… read more here.
Keywords: actin bundles; domain efa6a; terminal domain; efa6 ... See more keywords
mDia1/3 generate cortical F-actin meshwork in Sertoli cells that is continuous with contractile F-actin bundles and indispensable for spermatogenesis and male fertility
Sign Up to like & getrecommendations! Published in 2018 at "PLoS Biology"
DOI: 10.1371/journal.pbio.2004874
Abstract: Formin is one of the two major classes of actin binding proteins (ABPs) with nucleation and polymerization activity. However, despite advances in our understanding of its biochemical activity, whether and how formins generate specific architecture… read more here.
Keywords: continuous contractile; actin; actin meshwork; sertoli cells ... See more keywords
Remarkable structural transformations of actin bundles are driven by their initial polarity, motor activity, crosslinking, and filament treadmilling
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1007156
Abstract: Bundled actin structures play a key role in maintaining cellular shape, in aiding force transmission to and from extracellular substrates, and in affecting cellular motility. Recent studies have also brought to light new details on… read more here.
Keywords: remarkable structural; network; transformations actin; actin bundles ... See more keywords
Biomechanical Aspects of Actin Bundle Dynamics
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.00422
Abstract: Lamellipodial and filopodial protrusions are two of the main aggregate types of filamentous actin in living cells. Even though filopodia are essential to a range of vital cell functions, the mechanisms leading to their formation… read more here.
Keywords: biomechanical aspects; actin; actin bundle; actin bundles ... See more keywords
The Chlamydia trachomatis Early Effector Tarp Outcompetes Fascin in Forming F-Actin Bundles In Vivo
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.811407
Abstract: The intracellular pathogen Chlamydia trachomatis secretes multiple early effectors into the host cell to promote invasion. A key early effector during host cell entry, Tarp (translocated actin-recruiting phosphoprotein) is comprised of multiple protein domains known… read more here.
Keywords: actin bundles; actin; chlamydia trachomatis; tarp ... See more keywords
Actin Bundles Dynamics and Architecture
Sign Up to like & getrecommendations! Published in 2023 at "Biomolecules"
DOI: 10.3390/biom13030450
Abstract: Cells use the actin cytoskeleton for many of their functions, including their division, adhesion, mechanosensing, endo- and phagocytosis, migration, and invasion. Actin bundles are the main constituent of actin-rich structures involved in these processes. An… read more here.
Keywords: actin bundles; dynamics architecture; microscopy; actin ... See more keywords
Actin Bundles in The Pollen Tube
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms19123710
Abstract: The angiosperm pollen tube delivers two sperm cells into the embryo sac through a unique growth strategy, named tip growth, to accomplish fertilization. A great deal of experiments have demonstrated that actin bundles play a… read more here.
Keywords: actin; pollen tubes; bundles pollen; actin bundles ... See more keywords