Optogenetic control of receptors reveals distinct roles for actin- and Cdc42-dependent negative signals in chemotactic signal processing
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DOI: 10.1038/s41467-021-26371-z
Abstract: During chemotaxis, neutrophils use cell surface G Protein Coupled Receptors to detect chemoattractant gradients. The downstream signaling system is wired with multiple feedback loops that amplify weak inputs and promote spatial separation of cell front… read more here.
Keywords: actin cdc42; processing; negative signals; optogenetic control ... See more keywords