Cancer cells suppress NK cell activity by actin-driven polarization of inhibitory ligands to the immunological synapse
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DOI: 10.1073/pnas.2503259122
Abstract: Significance Our findings provide insights into previously uncharacterized dynamics at the cancer cell–cytotoxic lymphocyte interface, uncovering a critical mechanism by which actin cytoskeleton remodeling at the cancer cell side promotes resistance to natural killer (NK)… read more here.
Keywords: cancer; driven polarization; immunological synapse; actin driven ... See more keywords