Unique and redundant functions of cytoplasmic actins and nonmuscle myosin II isoforms at epithelial junctions
Sign Up to like & getrecommendations! Published in 2022 at "Annals of the New York Academy of Sciences"
DOI: 10.1111/nyas.14808
Abstract: The integrity and functions of epithelial barriers depend on the formation of adherens junctions (AJs) and tight junctions (TJs). A characteristic feature of AJs and TJs is their association with the cortical cytoskeleton composed of… read more here.
Keywords: actin isoforms; redundant functions; myosin; unique redundant ... See more keywords
Biological Role of Actin Isoforms in Mammalian Cells
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DOI: 10.1134/s0006297919060014
Abstract: Actin plays an important role in cellular adhesion, muscle and non-muscle contractility, migration, polarization, mitosis, and meiosis. Investigation of specific mechanisms underlying these processes is essential not only for fundamental research but also for clinical… read more here.
Keywords: actin isoforms; actin; biological role; role actin ... See more keywords
Pick-ya actin – a method to purify actin isoforms with bespoke key post-translational modifications
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cell Science"
DOI: 10.1242/jcs.241406
Abstract: ABSTRACT Actin is one of the most abundant eukaryotic cytoskeletal polymer-forming proteins, which, in the filamentous form, regulates a number of physiological processes, ranging from cell division and migration to development and tissue function. Actins… read more here.
Keywords: actin; post translational; method; actin isoforms ... See more keywords
Colocalization Analysis of Cytoplasmic Actin Isoforms Distribution in Endothelial Cells
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DOI: 10.3390/biomedicines10123194
Abstract: Actin cytoskeleton is an essential component of living cells and plays a decisive role in many cellular processes. In mammals, β- and γ-actin are cytoplasmic actin isoforms in non-muscle cells. Despite minor differences in the… read more here.
Keywords: actin isoforms; cell; colocalization; endothelial cells ... See more keywords
Structural insights into actin isoforms
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DOI: 10.7554/elife.82015
Abstract: Actin isoforms organize into distinct networks that are essential for the normal function of eukaryotic cells. Despite a high level of sequence and structure conservation, subtle differences in their design principles determine the interaction with… read more here.
Keywords: actin isoforms; structural insights; actin; actin actin ... See more keywords