Targeting the actin nucleation promoting factor WASp provides a therapeutic approach for hematopoietic malignancies
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DOI: 10.1038/s41467-021-25842-7
Abstract: Cancer cells depend on actin cytoskeleton rearrangement to carry out hallmark malignant functions including activation, proliferation, migration and invasiveness. Wiskott–Aldrich Syndrome protein (WASp) is an actin nucleation-promoting factor and is a key regulator of actin… read more here.
Keywords: nucleation promoting; hematopoietic malignancies; actin nucleation; promoting factor ... See more keywords