Helical structure of actin stress fibers and its possible contribution to inducing their direction-selective disassembly upon cell shortening
Sign Up to like & getrecommendations! Published in 2019 at "Biomechanics and Modeling in Mechanobiology"
DOI: 10.1007/s10237-019-01228-z
Abstract: Mechanisms of the assembly of actin stress fibers (SFs) have been extensively studied, while those of the disassembly—particularly cell shortening-induced ones—remain unclear. Here, we show that SFs have helical structures composed of multi-subbundles, and they… read more here.
Keywords: helical structure; upon cell; stress fibers; cell shortening ... See more keywords
Topography on a subcellular scale modulates cellular adhesions and actin stress fiber dynamics in tumor associated fibroblasts.
Sign Up to like & getrecommendations! Published in 2017 at "Physical biology"
DOI: 10.1088/1478-3975/aa7acc
Abstract: Cells can sense and adapt to mechanical properties of their environment. The local geometry of the extracellular matrix, such as its topography, has been shown to modulate cell morphology, migration, and proliferation. Here we investigate… read more here.
Keywords: topography; stress fiber; tumor associated; subcellular scale ... See more keywords
Automated segmentation and quantification of actin stress fibres undergoing experimentally induced changes
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Microscopy"
DOI: 10.1111/jmi.12593
Abstract: The actin cytoskeleton is a main component of cells and it is crucially involved in many physiological processes, e.g. cell motility. Changes in the actin organization can be effected by diseases or vice versa. Due… read more here.
Keywords: actin cytoskeleton; experimentally induced; stress; actin stress ... See more keywords
Type III Collagen is Required for Adipogenesis and Actin Stress Fibre Formation in 3T3-L1 Preadipocytes
Sign Up to like & getrecommendations! Published in 2021 at "Biomolecules"
DOI: 10.3390/biom11020156
Abstract: GPR56 is required for the adipogenesis of preadipocytes, and the role of one of its ligands, type III collagen (ColIII), was investigated here. ColIII expression was examined by reverse transcription quantitative polymerase chain reaction, immunoblotting… read more here.
Keywords: collagen; required adipogenesis; adipogenesis; 3t3 cells ... See more keywords
Actin Stress Fibers Response and Adaptation under Stretch
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23095095
Abstract: One of the many effects of soft tissues under mechanical solicitation in the cellular damage produced by highly localized strain. Here, we study the response of peripheral stress fibers (SFs) to external stretch in mammalian… read more here.
Keywords: stretch; fibers response; stress fibers; response ... See more keywords