A phosphoinositide-based model of actin waves in frustrated phagocytosis.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of theoretical biology"
DOI: 10.1016/j.jtbi.2021.110764
Abstract: Phagocytosis is a complex process by which phagocytes such as lymphocytes or macrophages engulf and destroy foreign bodies called pathogens in a tissue. The process is triggered by the detection of antibodies that trigger signaling… read more here.
Keywords: model actin; actin waves; phagocytosis; model ... See more keywords
Neuronal growth from a volume perspective
Sign Up to like & getrecommendations! Published in 2020 at "Physical Biology"
DOI: 10.1088/1478-3975/abc79c
Abstract: Microfluidic-based fluorescent exclusion method allows to tackle the issue of neuronal growth from a volume perspective. Based on this technology, we studied the two main actin-rich structures accompanying the early stages of neuron development, i.e.… read more here.
Keywords: neuronal growth; actin waves; volume; growth volume ... See more keywords
Actin waves transport RanGTP to the neurite tip to regulate non-centrosomal microtubules in neurons
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cell Science"
DOI: 10.1242/jcs.241992
Abstract: ABSTRACT Microtubules (MTs) are the most abundant cytoskeleton in neurons, and control multiple facets of their development. While the MT-organizing center (MTOC) in mitotic cells is typically located at the centrosome, the MTOC in neurons… read more here.
Keywords: transport rangtp; neurite tip; actin waves; non centrosomal ... See more keywords
Signaling and actin waves at a glance
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Cell Science"
DOI: 10.1242/jcs.263634
Abstract: ABSTRACT Waves of signaling and cytoskeletal components, which can be easily seen propagating on the ventral surface of a cell, are a systemic feature of biochemical networks that define the spatiotemporal dynamics of diverse cell… read more here.
Keywords: signaling actin; cell; actin waves; waves glance ... See more keywords
Two distinct actin waves correlated with turns-and-runs of crawling microglia
Sign Up to like & getrecommendations! Published in 2019 at "PLoS ONE"
DOI: 10.1371/journal.pone.0220810
Abstract: Freely crawling cells are often viewed as randomly moving Brownian particles but they generally exhibit some directional persistence. This property is often related to their zigzag motile behaviors that can be described as a noisy… read more here.
Keywords: actin waves; microscopy; peripheral ruffles; cell ... See more keywords
Geometrical Determinants of Neuronal Actin Waves
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2017.00086
Abstract: Hippocampal neurons produce in their early stages of growth propagative, actin-rich dynamical structures called actin waves. The directional motion of actin waves from the soma to the tip of neuronal extensions has been associated with… read more here.
Keywords: actin waves; neuronal actin; actin; actin wave ... See more keywords
Formation of Membrane Domains via Actin Waves: A Fundamental Principle in the Generation of Dynamic Structures in Phagocytes
Sign Up to like & getrecommendations! Published in 2025 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms26104759
Abstract: Phagocytes carry out their functions by organizing new subcellular structures. During phagocytosis, macrophages internalize and degrade pathogens and apoptotic cells by forming the phagocytic cup and phagosome. Osteoclasts resorb bone by forming the sealing zone… read more here.
Keywords: actin waves; dynamic structures; actin; formation membrane ... See more keywords