S137 Short-acting and long-acting β2-agonists upregulate asthma-relevant pro-inflammatory mediators in human airway epithelial cells while short-acting muscarinic antagonists do not
Sign Up to like & getrecommendations! Published in 2019 at "Thorax"
DOI: 10.1136/thorax-2019-btsabstracts2019.143
Abstract: Introduction and objectives Despite their undoubted benefits, increased mortality is associated with overuse of short-acting β2-agonists (SABAs) and with using long-acting β2-agonists (LABAs) in the absence of inhaled corticosteroids (ICS). Mechanisms underlying these adverse effects… read more here.
Keywords: asthma relevant; short acting; epithelial cells; significant induction ... See more keywords
It is time to end our love affair with short-acting β2-agonists in asthma? Yes
Sign Up to like & getrecommendations! Published in 2022 at "ERJ Open Research"
DOI: 10.1183/23120541.00555-2022
Abstract: I read with interest the editorial by Crooks and Faruqi [1]. I agree with almost all of the concepts; however, given my experience, I must question why the scientific community does not take a drastic… read more here.
Keywords: time; time end; acting agonists; love affair ... See more keywords
Short-acting β2-agonists (SABA) bronchodilator sales and outdoor mould in central France
Sign Up to like & getrecommendations! Published in 2019 at "Clinical and Translational Allergy"
DOI: 10.1186/s13601-019-0296-1
Abstract: BackgroundTemporal ecological studies have shown that outdoor moulds are associated with severe asthma exacerbations, as emergency department visits or hospitalisations. The aim of this was to assess the associations between daily sales of short-acting β2-agonists… read more here.
Keywords: central france; agonists saba; acting agonists; short acting ... See more keywords
Association of Inhaled Corticosteroids and Long-Acting β-Agonists as Controller and Quick Relief Therapy With Exacerbations and Symptom Control in Persistent Asthma: A Systematic Review and Meta-analysis
Sign Up to like & getrecommendations! Published in 2018 at "Pediatrics"
DOI: 10.1542/peds.2018-2420nnnn
Abstract: DM Sobieraj, ER Weeda, E Nguyen. JAMA. 2018;319(14):1485–1496 Because of the rapid onset of action of the long-acting β-agonist (LABA) formoterol, it has been hypothesized that the combined use of formoterol and inhaled corticosteroid (ICS)… read more here.
Keywords: relief; long acting; controller quick; acting agonists ... See more keywords
A Cross-Sectional Study on Prescription Patterns of Short-Acting β2-Agonists in Patients with Asthma: Results from the SABINA III Colombia Cohort
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Asthma and Allergy"
DOI: 10.2147/jaa.s365009
Abstract: Purpose Overuse of short-acting β2-agonists (SABAs) for asthma is associated with a significant increase in exacerbations and healthcare resource use. However, limited data exist on the extent of SABA overuse outside of Europe and North… read more here.
Keywords: sabina iii; acting agonists; prescription; asthma ... See more keywords