Fast-acting antidepressant-like effects of ketamine in aged male rats
Sign Up to like & getrecommendations! Published in 2024 at "Pharmacological Reports"
DOI: 10.1007/s43440-024-00636-y
Abstract: The aging process causes anatomical and physiological changes that predispose to the development of late-life depression while reduces the efficacy of classical antidepressants. Novel fast-acting antidepressants such as ketamine might be good candidates to be… read more here.
Keywords: fast acting; effects ketamine; like effects; acting antidepressant ... See more keywords
Neurobiology of the Rapid-Acting Antidepressant Effects of Ketamine: Impact and Opportunities
Sign Up to like & getrecommendations! Published in 2021 at "Biological Psychiatry"
DOI: 10.1016/j.biopsych.2020.12.006
Abstract: The discovery of the rapid-acting antidepressant effects of ketamine has 1) led to a paradigm shift in our perception of what is possible in treating severe depression; 2) spurred a wave of basic, translation, and… read more here.
Keywords: rapid acting; pathology; effects ketamine; neurobiology ... See more keywords
Rapid-acting antidepressant drugs modulate affective bias in rats
Sign Up to like & getrecommendations! Published in 2024 at "Science translational medicine"
DOI: 10.1126/scitranslmed.adi2403
Abstract: How rapid-acting antidepressants (RAADs), such as ketamine, induce immediate and sustained improvements in mood in patients with major depressive disorder (MDD) is poorly understood. A core feature of MDD is the prevalence of cognitive processing… read more here.
Keywords: rapid acting; acting antidepressant; bias; affective bias ... See more keywords