Association of Long-Acting Injectable Antipsychotics and Oral Antipsychotics With Disease Relapse, Health Care Use, and Adverse Events Among People With Schizophrenia
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.24163
Abstract: Key Points Question Are long-acting injectable antipsychotics (LAIAs) associated with a lower risk of disease relapse, health care use, and adverse events compared with oral antipsychotics among people in Hong Kong with schizophrenia? Findings In… read more here.
Keywords: oral antipsychotics; injectable antipsychotics; acting injectable; long acting ... See more keywords
Model‐Informed Drug Development for Long‐Acting Injectable Products: Summary of American College of Clinical Pharmacology Symposium
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.928
Abstract: Poor adherence to prescribed medications significantly impacts the U.S. health care system.1–4 Given the human and financial consequences, the development of strategies for improving adherence to prescribed medications is imperative. Long-acting injectable (LAI) drug products… read more here.
Keywords: drug development; long acting; drug; pharmacology ... See more keywords
Modeling Complex Pharmacokinetics of Long‐Acting Injectable Products Using Convolution‐Based Models With Nonparametric Input Functions
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Pharmacology"
DOI: 10.1002/jcph.1842
Abstract: The interest in the development and the therapeutic use of long‐acting injectable (LAI) products for chronic or long‐term treatments has grown exponentially. The complexity and the multiphase drug release process represent serious issues for an… read more here.
Keywords: long acting; convolution based; lai products; convolution ... See more keywords
Long‐acting injectable ART to advance health equity: a descriptive analysis of US clinic perspectives on barriers, needed support and programme goals for implementation from applications to the ALAI UP Project
Sign Up to like & getrecommendations! Published in 2024 at "Journal of the International AIDS Society"
DOI: 10.1002/jia2.26282
Abstract: Approval of the first long‐acting injectable antiretroviral therapy (LAI ART) medication heralded a new era of HIV treatment. However, the years since approval have been marked by implementation challenges. The “Accelerating Implementation of Multilevel Strategies… read more here.
Keywords: long acting; acting injectable; implementation; art ... See more keywords
Awareness and intention to use event‐driven and long‐acting injectable pre‐exposure prophylaxis among adolescent and young men who have sex with men and transgender women in Brazil: a cross‐sectional study
Sign Up to like & getrecommendations! Published in 2025 at "Journal of the International AIDS Society"
DOI: 10.1002/jia2.26479
Abstract: New pre‐exposure prophylaxis (PrEP) options, including event‐driven and long‐acting injectable, may enhance HIV prevention strategies among adolescents and youth. This study examined awareness and intention to use event‐driven and long‐acting injectable PrEP, along with associated… read more here.
Keywords: long acting; acting injectable; event driven; driven long ... See more keywords
Evaluation of the treatment of equine glandular gastric disease with either long‐acting‐injectable or oral omeprazole
Sign Up to like & getrecommendations! Published in 2022 at "Veterinary Medicine and Science"
DOI: 10.1002/vms3.728
Abstract: Abstract Background Equine glandular gastric disease (EGGD) is common in domesticated horses and can be challenging to treat. Oral omeprazole (ORLO) is used widely but the clinical response is frequently poor. Objectives To compare rates… read more here.
Keywords: equine glandular; glandular gastric; acting injectable; long acting ... See more keywords
Recovery-Oriented Outcomes Associated with Long-Acting Injectable Antipsychotics in an Urban Safety-Net Population
Sign Up to like & getrecommendations! Published in 2019 at "Community Mental Health Journal"
DOI: 10.1007/s10597-019-00412-w
Abstract: This study examined whether transitioning patients from oral antipsychotics (POs) to long-acting injectable antipsychotics (LAIs) helps patients achieve recovery-oriented goals. Data was extracted from San Francisco County’s electronic medical record system for this retrospective pre-post… read more here.
Keywords: injectable antipsychotics; recovery; long acting; safety net ... See more keywords
Real-World Effectiveness of Long-Acting Injectable and Oral Antipsychotic Agents in US Medicare Patients with Schizophrenia
Sign Up to like & getrecommendations! Published in 2025 at "Advances in Therapy"
DOI: 10.1007/s12325-024-03075-6
Abstract: Daily oral antipsychotics (OAPs) are the mainstay of schizophrenia treatment; however, long-acting injectable antipsychotics (LAIs) are associated with better treatment adherence and improved outcomes. This study assessed the real-world comparative effectiveness of LAIs and daily… read more here.
Keywords: treatment; long acting; acting injectable; real world ... See more keywords
Long acting injectable formulations: the state of the arts and challenges of poly(lactic-co-glycolic acid) microsphere, hydrogel, organogel and liquid crystal
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pharmaceutical Investigation"
DOI: 10.1007/s40005-019-00449-9
Abstract: BackgroundLong-acting injectable formulations (LAIFs) have received substantial attention recently due to their advantages over conventional formulations, including easy administration, continuous and controlled release of drug over months, and the ability to maintain drug concentrations within… read more here.
Keywords: poly lactic; injectable formulations; drug; lactic glycolic ... See more keywords
Expanding Treatment Opportunities: Reviewing the Current State of Injectable Antiretrovirals for Treatment of HIV
Sign Up to like & getrecommendations! Published in 2024 at "Infectious Diseases and Therapy"
DOI: 10.1007/s40121-024-01062-6
Abstract: Antiretroviral therapy has evolved significantly over the last 20–30 years, from requiring multiple tablets multiple times per day to single-tablet regimens and most recently, in 2021, long-acting injectable antiretrovirals. These long-acting antiretrovirals have expanded the… read more here.
Keywords: treatment; long acting; hiv; acting injectable ... See more keywords
Hospitalization Rates and Therapy Costs of German Schizophrenia Patients Who are Initiated on Long-Acting Injectable Medication: A Mirror-Image Study
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Drug Investigation"
DOI: 10.1007/s40261-020-00900-y
Abstract: Background Long-acting injectable (LAI) antipsychotics can reduce relapse, hospitalization, and costs in patients with schizophrenia. However, real-world evidence assessing the impact of treatment with LAIs in Germany is limited. Objective To provide updated evidence on… read more here.
Keywords: index; hospitalization; initiation; long acting ... See more keywords