Association of Long-Acting Injectable Antipsychotics and Oral Antipsychotics With Disease Relapse, Health Care Use, and Adverse Events Among People With Schizophrenia
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.24163
Abstract: Key Points Question Are long-acting injectable antipsychotics (LAIAs) associated with a lower risk of disease relapse, health care use, and adverse events compared with oral antipsychotics among people in Hong Kong with schizophrenia? Findings In… read more here.
Keywords: oral antipsychotics; injectable antipsychotics; acting injectable; long acting ... See more keywords
Model‐Informed Drug Development for Long‐Acting Injectable Products: Summary of American College of Clinical Pharmacology Symposium
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.928
Abstract: Poor adherence to prescribed medications significantly impacts the U.S. health care system.1–4 Given the human and financial consequences, the development of strategies for improving adherence to prescribed medications is imperative. Long-acting injectable (LAI) drug products… read more here.
Keywords: drug development; long acting; drug; pharmacology ... See more keywords
Modeling Complex Pharmacokinetics of Long‐Acting Injectable Products Using Convolution‐Based Models With Nonparametric Input Functions
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Pharmacology"
DOI: 10.1002/jcph.1842
Abstract: The interest in the development and the therapeutic use of long‐acting injectable (LAI) products for chronic or long‐term treatments has grown exponentially. The complexity and the multiphase drug release process represent serious issues for an… read more here.
Keywords: long acting; convolution based; lai products; convolution ... See more keywords
Evaluation of the treatment of equine glandular gastric disease with either long‐acting‐injectable or oral omeprazole
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DOI: 10.1002/vms3.728
Abstract: Abstract Background Equine glandular gastric disease (EGGD) is common in domesticated horses and can be challenging to treat. Oral omeprazole (ORLO) is used widely but the clinical response is frequently poor. Objectives To compare rates… read more here.
Keywords: equine glandular; glandular gastric; acting injectable; long acting ... See more keywords
Recovery-Oriented Outcomes Associated with Long-Acting Injectable Antipsychotics in an Urban Safety-Net Population
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DOI: 10.1007/s10597-019-00412-w
Abstract: This study examined whether transitioning patients from oral antipsychotics (POs) to long-acting injectable antipsychotics (LAIs) helps patients achieve recovery-oriented goals. Data was extracted from San Francisco County’s electronic medical record system for this retrospective pre-post… read more here.
Keywords: injectable antipsychotics; recovery; long acting; safety net ... See more keywords
Long acting injectable formulations: the state of the arts and challenges of poly(lactic-co-glycolic acid) microsphere, hydrogel, organogel and liquid crystal
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pharmaceutical Investigation"
DOI: 10.1007/s40005-019-00449-9
Abstract: BackgroundLong-acting injectable formulations (LAIFs) have received substantial attention recently due to their advantages over conventional formulations, including easy administration, continuous and controlled release of drug over months, and the ability to maintain drug concentrations within… read more here.
Keywords: poly lactic; injectable formulations; drug; lactic glycolic ... See more keywords
Hospitalization Rates and Therapy Costs of German Schizophrenia Patients Who are Initiated on Long-Acting Injectable Medication: A Mirror-Image Study
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DOI: 10.1007/s40261-020-00900-y
Abstract: Background Long-acting injectable (LAI) antipsychotics can reduce relapse, hospitalization, and costs in patients with schizophrenia. However, real-world evidence assessing the impact of treatment with LAIs in Germany is limited. Objective To provide updated evidence on… read more here.
Keywords: index; hospitalization; initiation; long acting ... See more keywords
Long-Acting Injectable Antipsychotics: Analysis of Prescription Patterns and Patient Characteristics in Mental Health from a Spanish Real-World Study
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Drug Investigation"
DOI: 10.1007/s40261-020-00913-7
Abstract: Background and Objective Long-acting injectable antipsychotics (LAIs) have been widely studied in schizophrenia and evidence suggests that they could be also used for the treatment of bipolar and schizoaffective disorders. Nonetheless, there are no studies… read more here.
Keywords: injectable antipsychotics; aripiprazole monthly; weekly lais; long acting ... See more keywords
Long acting injectable aripiprazole: An observational study
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DOI: 10.1016/j.eurpsy.2017.01.1403
Abstract: Introduction Several trials have shown the efficacy of long acting injectable (LAI) second-generation anti-psychotics compared with other anti-psychotics. LAI aripiprazole is a novel therapeutic tool in the management of patients with schizophrenia. Aims The present… read more here.
Keywords: long acting; lai aripiprazole; treatment; study ... See more keywords
Long-acting injectable buprenorphine for opioid use disorder: A systematic review of impact of use on social determinants of health.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of substance abuse treatment"
DOI: 10.1016/j.jsat.2022.108776
Abstract: OBJECTIVES This systematic review synthesizes evidence on both the effects and perspectives of the use of novel long-acting injectable buprenorphine (LAIB) as part of medication-assisted treatment (MAT) and its impact on social determinants of health… read more here.
Keywords: injectable buprenorphine; social determinants; acting injectable; systematic review ... See more keywords
Letter to the Editor: Is paliperidone palmitate more effective than other long-acting injectable antipsychotics?
Sign Up to like & getrecommendations! Published in 2018 at "Psychological Medicine"
DOI: 10.1017/s0033291718001319
Abstract: © Cambridge University Press 2018. This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/ by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the… read more here.
Keywords: injectable antipsychotics; effective long; long acting; palmitate effective ... See more keywords