Opportunities to optimise direct‐acting oral anticoagulants
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DOI: 10.1002/psb.1874
Abstract: The newer direct‐acting oral anticoagulants (DOACs) – apixaban, dabigatran, edoxaban, rivaroxaban – offer many advantages over older anticoagulants such as warfarin. However, in order to optimise their benefits, it is important that patients taking them… read more here.
Keywords: acting oral; oral anticoagulants; direct acting; opportunities optimise ... See more keywords
Effect of a novel pharmacist-led reporting system on appropriate use of direct-acting oral anticoagulants (DOACs) in a patient-centered medical home
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Thrombosis and Thrombolysis"
DOI: 10.1007/s11239-020-02223-3
Abstract: Recent analyses demonstrate roughly 16–24% of patients taking direct-acting oral anticoagulants (DOACs) are prescribed an inappropriate dose, exposing patients to increased risk of thrombosis or bleeding. The use of reporting systems in the outpatient setting… read more here.
Keywords: acting oral; oral anticoagulants; effect novel; novel pharmacist ... See more keywords
[Use of direct-acting oral anticoagulants in Primary Care in Spain. Positioning statement by SEMERGEN on the current situation].
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DOI: 10.1016/j.semerg.2019.06.002
Abstract: The direct-acting oral anticoagulants (DOACs) are drugs that have been shown to have a safety profile superior to the vitaminK antagonists (VKA). The prescribing of DOACs in Spain is subject to approval in the form… read more here.
Keywords: acting oral; use; semergen; primary care ... See more keywords
Real-world comparison of direct-acting oral anticoagulants and vitamin K antagonists in chronic kidney disease: a systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2021 at "Expert Review of Hematology"
DOI: 10.1080/17474086.2021.1920012
Abstract: ABSTRACT Background: No clear clinical guidelines exist on anticoagulant use for chronic kidney disease (CKD) patients. We compared the efficacy and safety of direct-acting oral anticoagulants (DOACs) vs. vitamin K antagonists (VKA) in patients with… read more here.
Keywords: acting oral; chronic kidney; oral anticoagulants; direct acting ... See more keywords
A Review of Direct-acting Oral Anticoagulants and Their Use in Solid Organ Transplantation
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DOI: 10.1097/tp.0000000000004195
Abstract: Direct-acting oral anticoagulant (DOAC) use has increased dramatically since their introduction because of the growing evidence of proven efficacy and enhanced safety compared with warfarin and the low-molecular-weight heparins in the general population. Unfortunately, there… read more here.
Keywords: acting oral; transplantation review; solid organ; direct acting ... See more keywords
Risk of myocardial infarction in patients with atrial fibrillation using vitamin K antagonists, aspirin or direct acting oral anticoagulants
Sign Up to like & getrecommendations! Published in 2017 at "British Journal of Clinical Pharmacology"
DOI: 10.1111/bcp.13264
Abstract: AIM Direct-acting oral anticoagulants (DOACs) have become available for the prevention of stroke in patients with atrial fibrillation (AF). Conflicting results have been published on the risk of acute myocardial infarction (AMI) with the use… read more here.
Keywords: atrial fibrillation; acting oral; oral anticoagulants; myocardial infarction ... See more keywords
A systematic review of clinicians' views and experiences of direct‐acting oral anticoagulants in the management of nonvalvular atrial fibrillation
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Clinical Pharmacology"
DOI: 10.1111/bcp.13739
Abstract: AIMS While a plethora of systematic reviews have provided evidence of efficacy, effectiveness and safety of direct-acting oral anticoagulants (DOACs) in the management of nonvalvular atrial fibrillation, there has been little emphasis on clinicians' perspectives.… read more here.
Keywords: acting oral; views experiences; oral anticoagulants; management ... See more keywords
Prescribing direct‐acting oral anticoagulants – Mind the evidence gap
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DOI: 10.1111/bcp.15450
Abstract: Direct‐acting oral anticoagulants (DOACs) are licensed for the prevention of thromboembolism in non‐valvular atrial fibrillation, amongst other indications. Prescribers use information derived from the summary of product characteristics which is based on the key trials… read more here.
Keywords: prescribing direct; acting oral; evidence; direct acting ... See more keywords
Dilemmas Related to Direct-Acting Oral Anticoagulant Administration in Patients With Extreme Obesity
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DOI: 10.1177/10600280221130456
Abstract: Objective: The objective of the study was to discuss the controversies surrounding the use and dosing of direct-acting oral anticoagulants (DOACs) in obese patients recognizing the limitations of the existing evidence base that preclude strong… read more here.
Keywords: patients extreme; obese patients; acting oral; dilemmas related ... See more keywords
Prescribing Patterns of Direct-Acting Oral Anticoagulants in Patients With Atrial Fibrillation and Chronic Kidney Disease: A Retrospective Cohort Analysis
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DOI: 10.1177/10742484221142220
Abstract: Background: The association of patient and prescriber characteristics with use of warfarin versus direct-acting oral anticoagulants (DOACs) in patients with atrial fibrillation (AF) and chronic kidney disease (CKD) is not well studied. Methods: The 20%… read more here.
Keywords: patients atrial; fibrillation chronic; acting oral; direct acting ... See more keywords
Prior Authorization and Canadian Public Utilization of Direct-Acting Oral Anticoagulants
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DOI: 10.12927/hcpol.2017.25321
Abstract: Purpose: Provincial public drug formularies in Canada have different mechanisms for reimbursement of direct-acting oral anticoagulants (DOACs). We investigate how these differences influence DOAC utilization and expenditure across the country. Methods: We conducted a population-based,… read more here.
Keywords: utilization; acting oral; oral anticoagulants; direct acting ... See more keywords