Interpreting in vitro Release Performance from Long-Acting Parenteral Nanosuspensions using USP-4 Dissolution and Spectroscopic Techniques.
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DOI: 10.1021/acs.molpharmaceut.0c00208
Abstract: Injectable sustained release dosage forms have emerged as desirable therapeutic routes for patients that require life-long treatments. The prevalence of drug molecules with low aqueous solubility and bioavailability has added momentum towards the development of… read more here.
Keywords: vitro release; long acting; usp dissolution; acting parenteral ... See more keywords
Pharmacokinetics, safety and tolerability of long‐acting parenteral intramuscular injection formulations of doravirine
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Pharmacy and Therapeutics"
DOI: 10.1111/jcpt.13182
Abstract: Doravirine is a non‐nucleoside reverse transcriptase inhibitor indicated for the treatment of human immunodeficiency virus (HIV)‐1 infection. This phase 1 study in healthy adults investigated the pharmacokinetics, safety and tolerability of long‐acting parenteral (LAP) microsuspension… read more here.
Keywords: long acting; safety tolerability; acting parenteral; pharmacokinetics safety ... See more keywords