A Cell-based Screen in Actinomyces oris to Identify Sortase Inhibitors
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DOI: 10.1038/s41598-020-65256-x
Abstract: Sortase enzymes are attractive antivirulence drug targets that attach virulence factors to the surface of Staphylococcus aureus and other medically significant bacterial pathogens. Prior efforts to discover a useful sortase inhibitor have relied upon an… read more here.
Keywords: sortase inhibitors; screen actinomyces; cell based; based screen ... See more keywords
Interactions between Streptococcus oralis, Actinomyces oris, and Candida albicans in the development of multispecies oral microbial biofilms on salivary pellicle
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DOI: 10.1111/omi.12154
Abstract: The fungus Candida albicans is carried orally and causes a range of superficial infections that may become systemic. Oral bacteria Actinomyces oris and Streptococcus oralis are abundant in early dental plaque and on oral mucosa.… read more here.
Keywords: streptococcus oralis; interactions streptococcus; actinomyces oris; oralis actinomyces ... See more keywords