High-Content Screening of Raw Actinomycete Extracts for the Identification of Antituberculosis Activities
Sign Up to like & getrecommendations! Published in 2017 at "SLAS Discovery"
DOI: 10.1177/1087057116675887
Abstract: The feasibility and relevance of screening a library of raw actinomycete extracts (ECUM library) for the identification of antituberculosis activities was assessed on 11,088 extracts using a multiple-screening approach. Each extract was first tested at… read more here.
Keywords: actinomycete extracts; raw actinomycete; antituberculosis activities; identification antituberculosis ... See more keywords
Screening of Protein Tyrosine Phosphatase 1B Inhibitors from Actinomycete Extracts Using Recombinant Saccharomyces cerevisiae
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Microbiology and Biotechnology"
DOI: 10.4014/jmb.2502.02001
Abstract: Protein tyrosine phosphatase 1B (PTP1B) removes phosphate groups from phosphorylated tyrosine proteins in human cells, particularly in the insulin and leptin signaling pathways. It is a key drug target for ailments such as type 2… read more here.
Keywords: saccharomyces cerevisiae; ptp1b; actinomycete extracts; recombinant saccharomyces ... See more keywords