The NLRP3 inflammasome: Mechanism of action, role in disease and therapies.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular aspects of medicine"
DOI: 10.1016/j.mam.2020.100889
Abstract: NLRP3 is the best characterized cytosolic nod-like pattern recognition receptor which can detect microbial motifs, endogenous danger and stress signals. Activation of NLRP3 leads to the formation of a cytosolic multiprotein signaling complex called the… read more here.
Keywords: inflammasome mechanism; mechanism; nlrp3 inflammasome; action role ... See more keywords
'Lights, squaraines, action!' - the role of squaraine dyes in photodynamic therapy.
Sign Up to like & getrecommendations! Published in 2022 at "Future medicinal chemistry"
DOI: 10.4155/fmc-2022-0112
Abstract: Since they were first synthesized in 1965 by Treibs and Jacob, squaraine dyes have revolutionized the polymethine dyes' 'universe' and their potential applications due to their indisputable physical, chemical and biological properties. After 30 years and… read more here.
Keywords: action role; squaraines action; squaraine dyes; photodynamic therapy ... See more keywords