Identification of putative actionable alterations in clinically relevant genes in breast cancer.
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DOI: 10.1038/s41416-021-01522-7
Abstract: BACKGROUND Individualising treatment in breast cancer requires effective predictive biomarkers. While relatively few genomic aberrations are clinically relevant, there is a need for characterising patients across different subtypes to identify actionable alterations. METHODS We identified… read more here.
Keywords: actionable alterations; putative actionable; breast cancer; clinically relevant ... See more keywords
Precision medicine and actionable alterations in lung cancer: A single institution experience
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DOI: 10.1371/journal.pone.0228188
Abstract: Objectives Oncology has become more reliant on new testing methods and a greater use of electronic medical records, which provide a plethora of information available to physicians and researchers. However, to take advantage of vital… read more here.
Keywords: actionable alterations; medicine; precision medicine; median months ... See more keywords
Characteristics of Genomic Alterations in Pericardial Effusion of Advanced Non-small Cell Lung Cancer
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DOI: 10.3389/fgene.2022.850290
Abstract: Background: The feasibility and value of pericardial effusion as a liquid biopsy sample for actionable alteration detection in patients with non-small cell lung cancer (NSCLC) has not been adequately investigated. Here, we aim to reveal… read more here.
Keywords: non small; cfdna; pericardial effusion; small cell ... See more keywords
Comprehensive Analysis of Genomic Alterations in Hepatoid Adenocarcinoma of the Stomach and Identification of Clinically Actionable Alterations
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DOI: 10.3390/cancers14163849
Abstract: Simple Summary Hepatoid adenocarcinoma of the stomach (HAS) is a subset of gastric cancer (GC) histologically characterized by hepatocellular carcinoma-like foci with or without alpha-fetoprotein secretion, which is easily misdiagnosed. Genomic alterations and potential targets… read more here.
Keywords: clinically actionable; adenocarcinoma stomach; genomic alterations; hepatoid adenocarcinoma ... See more keywords