Mycobacterial Membranes as Actionable Targets for Lipid-Centric Therapy in Tuberculosis.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.1c01870
Abstract: Infectious diseases remain significant health concerns worldwide, and resistance is particularly common in patients with tuberculosis caused by Mycobacterium tuberculosis. The development of anti-infectives with novel modes of action may help overcome resistance. In this… read more here.
Keywords: tuberculosis; membrane active; membranes actionable; mycobacterial membranes ... See more keywords
CCN proteins as potential actionable targets in scleroderma
Sign Up to like & getrecommendations! Published in 2019 at "Experimental Dermatology"
DOI: 10.1111/exd.13806
Abstract: Systemic sclerosis (SSc) is a complex autoimmune connective tissue disease combining inflammatory, vasculopathic and fibrotic manifestations. Skin features, which give their name to the disease and are considered as diagnostic as well as prognostic markers,… read more here.
Keywords: actionable targets; proteins potential; ccn proteins; potential actionable ... See more keywords