Rapid and Sensitive Detection of Cancer Cells with Activatable Fluorescent Probes for Enzyme Activity.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1258-3_17
Abstract: Fluorescence (FL)-guided detection of cancer is one of the most promising approaches to achieve intraoperative assessment of surgical margins. Enzymes, such as aminopeptidase, carboxypeptidase, and glycosidase, whose activities are increased in cancer, have attracted great… read more here.
Keywords: activatable fluorescent; rapid sensitive; cancer cells; cancer ... See more keywords
Thrombin-activatable fluorescent peptide incorporated gold nanoparticles for dual optical/computed tomography thrombus imaging.
Sign Up to like & getrecommendations! Published in 2018 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2017.10.017
Abstract: Thrombosis is an important pathophysiologic phenomenon in various cardiovascular diseases, which can lead to oxygen deprivation and infarction of tissues by generation of a thrombus. Thus, direct thrombus imaging can provide beneficial in diagnosis and… read more here.
Keywords: activatable fluorescent; peptide; thrombus imaging; thrombin activatable ... See more keywords
Cathepsin B Activatable Fluorescent Probe for Antitumor Efficiency Feedback: Attempt To Detect Certain Apoptotic Cells.
Sign Up to like & getrecommendations! Published in 2025 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.4c05649
Abstract: As many treatments kill tumor cells by inducing apoptosis, fluorescent probes that can detect apoptosis are crucial for effective feedback regarding tumor therapy outcomes (in particular, activatable probes for better imaging). Cathepsins are enzymes that… read more here.
Keywords: fluorescent; activatable fluorescent; fluorescent probe; tumor cells ... See more keywords
Activatable fluorescent probes for in situ imaging of enzymes.
Sign Up to like & getrecommendations! Published in 2021 at "Chemical Society reviews"
DOI: 10.1039/d1cs00543j
Abstract: As the main biomarkers of most diseases, enzymes play fundamental but extremely critical roles in biosystems. High-resolution studies of enzymes using activatable in situ fluorescence imaging may help to better elucidate their dynamics in living… read more here.
Keywords: high resolution; activatable fluorescent; fluorescent probes; situ imaging ... See more keywords
Dipeptidylpeptidase‐4‐targeted activatable fluorescent probes visualize senescent cells
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Science"
DOI: 10.1111/cas.16229
Abstract: Senescent cells promote cancer development and progression through chronic inflammation caused by a senescence‐associated secretory phenotype (SASP). Although various senotherapeutic strategies targeting senescent cells have been developed for the prevention and treatment of cancers, technology… read more here.
Keywords: dipeptidylpeptidase targeted; targeted activatable; senescent cells; activatable fluorescent ... See more keywords