In vivo imaging of senescent vascular cells in atherosclerotic mice using a β-galactosidase-activatable nanoprobe.
Sign Up to like & getrecommendations! Published in 2020 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.0c02670
Abstract: Senescence-associated diseases have severely diminished the quality of life and health of patients. However, a sensitive assay of these diseases remains limited due to a lack of straightforward methods. Considering that senescence-associated β-galactosidase (SA-β-Gal) is… read more here.
Keywords: activatable nanoprobe; imaging senescent; senescent cells; atherosclerotic mice ... See more keywords
Activatable Nanoprobe with Aggregation-Induced Dual Fluorescence and Photoacoustic Signal Enhancement for Tumor Precision Imaging and Radiotherapy.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c00340
Abstract: Owing to the high sensitivity and high spatial resolution, fluorescence (FL) imaging has been widely applied for visualizing biological processes. To gain insight into molecular events on deeper tissues, photoacoustic (PA) imaging with better deep-tissue… read more here.
Keywords: activatable nanoprobe; radiotherapy; enhancement; aggregation induced ... See more keywords
Quantitative hypoxia mapping using a self-calibrated activatable nanoprobe
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Nanobiotechnology"
DOI: 10.1186/s12951-022-01341-9
Abstract: Hypoxia is a distinguished hallmark of the tumor microenvironment. Hypoxic signaling affects multiple gene expressions, resulting in tumor invasion and metastasis. Quantification of hypoxic status although challenging, can be useful for monitoring tumor development and… read more here.
Keywords: tumor; activatable nanoprobe; self calibrated; calibrated activatable ... See more keywords