NAD(P)H: quinone oxidoreductase 1 activatable toll-like receptor 7/8 agonist designed for precise immunotherapy.
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DOI: 10.1039/d3cc00663h
Abstract: An NQO1-responsive precursor, named R848-QPA, has been developed to evoke an anti-tumor immune response. R848-QPA can induce innate immune activation when activated by overexpressed NQO1 in the tumor microenvironment while showing lower activity in NQO1-deprived… read more here.
Keywords: toll like; activatable toll; like receptor; oxidoreductase activatable ... See more keywords