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   Articles with "activate complement" as a keyword



Sub-visible Particles in IVIg Formulations Activate Complement in Human Serum.

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recommendations! Published in 2019 at "Journal of pharmaceutical sciences"

DOI: 10.1016/j.xphs.2019.10.041

Abstract: When administered intravenously, various particles and nanomedicines activate complement, potentially leading to infusion reactions and other adverse drug reactions. Particles form within formulations of therapeutic proteins due to stresses incurred during shipping, handling and administration… read more here.

Keywords: human serum; activate complement; sub visible; visible particles ... See more keywords
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Renal fibrosis: Pericytes activate complement in fibrosis

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recommendations! Published in 2017 at "Nature Reviews Nephrology"

DOI: 10.1038/nrneph.2017.49

Abstract: A need exists for biomarkers that can monitor transplant rejection. Now, Vallabhajosyula et al. show that, in a human-to-mouse xenogeneic islet transplant model, human exosomes (extracellular vesicles that are released by tissues) can be purified… read more here.

Keywords: fibrosis; pericytes activate; fibrosis pericytes; activate complement ... See more keywords
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Antigen-enabled facile preparation of MOF nanovaccine to activate the complement system for enhanced antigen-mediated immune response.

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recommendations! Published in 2019 at "Biomaterials science"

DOI: 10.1039/c9bm01145e

Abstract: Since current subunit vaccines are limited by a short half-life in vivo and weak immune responses when used alone without adjuvants, there is an unmet need for combing carriers with complement activation signals to interrupt… read more here.

Keywords: enabled facile; complement system; activate complement; antigen enabled ... See more keywords

Some Human Anti-Glycan Antibodies Lack the Ability to Activate the Complement System

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recommendations! Published in 2024 at "Antibodies"

DOI: 10.3390/antib13040105

Abstract: Background. Naturally occurring human antibodies against glycans recognize and quickly eliminate infectious bacteria, viruses and aberrantly glycosylated neoplastic malignant cells, and they often initiate processes that involve the complement system. Methods. Using a printed glycan… read more here.

Keywords: anti glycan; complement; glycan antibodies; activate complement ... See more keywords